2. Gene
  3. EMB - embigin Gene

EMB - embigin Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：嵌入

种属: Homo sapiens

同用名: GP70

基因 ID: 133418 | 基因类型: protein coding

关于 EMB

Cytogenetic location: 5q11.1 Genomic coordinates (GRCh38): 5:50,396,192-50,443,345 (from NCBI)

This gene has 5 transcripts (splice variants), 192 orthologues and 3 paralogues. Broad expression in bone marrow (RPKM 76.3), duodenum (RPKM 39.2) and 16 other tissues.

功能概要

该基因编码一种跨膜糖蛋白，它是免疫球蛋白超家族的一员。所编码的蛋白质可能通过介导细胞和细胞外基质之间的相互作用而参与细胞生长和发育。在 1 号染色体上发现了该基因的假基因。[RefSeq 提供，2009 年 1 月]

This gene encodes a Transmembrane Glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Jan 2009]

EMB 基因产物(1)

mRNA Protein Name
NM_198449.3 NP_940851.1 embigin precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
33961781 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

EMB 蛋白结构

Ig_2

Ig_2: Immunoglobulin domain (76 - 146)

I-set

I-set: Immunoglobulin I-set domain (161 - 254)

  • 0
  • 100
  • 200
  • 300
  • 327 a.a.
蛋白主名 其他名称

embigin

embigin homolog

EMB 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
EMB Q6PCB8 BCS1L Homo sapiens Q9Y276
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Splenic Manifestation Of Leukemia

Splenic Leukemia
Sporotrichosis

Rose Gardener'S Disease
Primary Systemic Mycosis
Conidiobolomycosis

Infection By Conidiobolus

Rhinoentomophthoromycosis

Entomophthoromycosis Conidiobolae
Subcutaneous Mycosis

Subcutaneous Fungal Disease
Null-Cell Leukemia

Null Cell Acute Lymphoblastic Leukemia

Null Cell Acute Lymphoblastic Leukaemia

Null-Cell Leukaemia
Acute Erythroid Leukemia

Acute Erythroleukemia

Di Guglielmo'S Syndrome

Aml M6

Acute Myeloid Leukemia Fab-M6

Acute Myeloid Leukemia M6

Erythroleukemia

Aml-M6

Acute Erythroleukemia M6a Subtype

Acute Erythroleukemia M6b Subtype

Di Guglielmo Syndrome

Acute Myeloid Leukemia, M6 Type

Acute Erythroblastic Leukemia

Acute Erythroleukemia - M6a Subtype

Acute Erythroleukemia - M6b Subtype

Acute Erythraemia And Erythroleukaemia

Acute Erythroid Leukaemia Without Mention Of Remission

Erythraemia

Erythraemic Myelosis

Erythroleukaemia

Acute Erythraemic Myelosis

Acute Erythraemia
Developmental And Epileptic Encephalopathy 24

DEE24

Epileptic Encephalopathy, Early Infantile, 24

Eiee24

Developmental And Epileptic Encephalopathy, 24

Early Infantile Epileptic Encephalopathy 24

Encephalopathy, Epileptic, Early Infantile, Type 24
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0535A Ethambutol dihydrochloride Inhibitor 99.91% 是
HY-B0535AR Ethambutol dihydrochloride (Standard) Inhibitor 99.87% 否
Clinical Phase
抗体抑制剂 (3)
目录号 产品名 作用方式
纯度 Phase
HY-P99455 Bafisontamab Inhibitor 99.9% Phase 3
HY-P990980 Cizutamig Inhibitor 95% Phase 2
HY-P990740 Fanastomig 95.478% Phase 2
Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-B0535S Ethambutol-d4 Inhibitor 98.12% 否
HY-RS15889 XPO1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-157352 Eosin-Methylene Blue Agar / 否
HY-157364 Levine Eosin-Methylene Blue Agar Medium / 否
HY-B0535AS Ethambutol-d4 dihydrochloride Inhibitor / 否
HY-B0535S1 Ethambutol-d10 Inhibitor 99.0% 否
HY-B0535S2 Ethambutol-d8 Inhibitor / 否
HY-RS04334 EMB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16761 Emb Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23200 Emb Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus EMB RGD RGD:621067
Mus musculus EMB MGD MGI:95321
Canis familiaris EMB VGNC VGNC:50876
Felis catus EMB VGNC VGNC:102194
Macaca mulatta EMB VGNC VGNC:72144
Macaca fascicularis EMB NCBI NCBI:101926123
Susscrofa domestica EMB NCBI
Leporidae EMB NCBI
Others EMB NCBI
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