2. Gene
  3. Dscam - DS cell adhesion molecule Gene

Dscam - DS cell adhesion molecule Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 4932410A21Rik

基因 ID: 13508 | 基因类型: protein coding

关于 Dscam

功能概要

Enables netrin receptor binding activity and protein tyrosine kinase binding activity. Involved in generation of neurons; negative regulation of cell adhesion; and netrin-activated signaling pathway. Acts upstream of or within dendrite morphogenesis; locomotory behavior; and post-embryonic retina morphogenesis in camera-type eye. Located in several cellular components, including dendrite; growth cone; and neuronal cell body. Is expressed in several structures, including central nervous system; peripheral nervous system; sensory organ; skin; and testis. Orthologous to human DSCAM (DS cell adhesion molecule). [provided by Alliance of Genome Resources, Apr 2022]

Dscam 基因产物(1)

mRNA Protein Name
NM_031174.4 NP_112451.1 cell adhesion molecule DSCAM precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables netrin receptor binding IPI
IPI: 通过物理相互作用推断
22685302 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18585357 MGI
enables protein tyrosine kinase binding IPI
IPI: 通过物理相互作用推断
22685302 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in axon guidance IDA
IDA: 通过直接分析推断
22685302 MGI
involved in axon guidance IGI
IGI: 通过遗传相互作用推断
22685302 MGI
acts upstream of or within dendrite morphogenesis IMP
IMP: 通过突变表型推断
18216855 MGI
involved in dendrite self-avoidance IMP
IMP: 通过突变表型推断
19945391 MGI
acts upstream of or within locomotory behavior IMP
IMP: 通过突变表型推断
18216855 MGI
involved in negative regulation of cell adhesion IMP
IMP: 通过突变表型推断
19945391 MGI
involved in netrin-activated signaling pathway IDA
IDA: 通过直接分析推断
22685302 MGI
involved in netrin-activated signaling pathway IGI
IGI: 通过遗传相互作用推断
22685302 MGI
involved in positive regulation of axon extension involved in axon guidance IDA
IDA: 通过直接分析推断
18585357 MGI
acts upstream of or within post-embryonic retina morphogenesis in camera-type eye IMP
IMP: 通过突变表型推断
18216855 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
19196994 MGI
located in dendrite IDA
IDA: 通过直接分析推断
22685302 MGI
located in growth cone IDA
IDA: 通过直接分析推断
19196994 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
22685302 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
19196994 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cell adhesion molecule DSCAM

Down syndrome cell adhesion molecule homolog

Dscam 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Dscam Q9ERC8 Dcc Mus musculus P70211
Anti Bait CoIP
18585357
种属间
Dscam Q9ERC8 NTN1 Gallus gallus Q90922
Anti Tag CoIP
18585357
种属间
Dscam Q9ERC8 NTN1 Gallus gallus Q90922
Anti Bait CoIP
18585357
种属间
Dscam Q9ERC8 NTN1 Gallus gallus Q90922
IF
18585357
种属间
Dscam Q9ERC8 Dcc Rattus norvegicus Q63155
Anti Tag CoIP
18585357
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04017 DSCAM Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21560 Dscam Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28078 Dscam Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dscam NCBI NCBI:1826
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