2. Gene
  3. Khk - ketohexokinase Gene

Khk - ketohexokinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 16548 | 基因类型: protein coding

关于 Khk

功能概要

Enables Ketohexokinase activity. Acts upstream of or within fructose metabolic process and regulation of glycogen metabolic process. Located in cytoplasm and nucleus. Is expressed in alimentary system; central nervous system; liver; and retina. Human ortholog(s) of this gene implicated in essential fructosuria. Orthologous to human KHK (Ketohexokinase). [provided by Alliance of Genome Resources, Apr 2022]

Khk 基因产物(4)

mRNA Protein Name
NM_001310524.1 NP_001297453.1 ketohexokinase isoform 1
NM_001310525.1 NP_001297454.1 ketohexokinase isoform 3
NM_001349066.1 NP_001335995.1 ketohexokinase isoform 4
NM_008439.4 NP_032465.2 ketohexokinase isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ketohexokinase activity IDA
IDA: 通过直接分析推断
15652177 MGI
enables ketohexokinase activity IMP
IMP: 通过突变表型推断
28194018 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in fructose catabolic process IDA
IDA: 通过直接分析推断
4343087 MGI
involved in fructose catabolic process IMP
IMP: 通过突变表型推断
23813872 MGI
involved in fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate IMP
IMP: 通过突变表型推断
23813872 MGI
acts upstream of or within fructose metabolic process IMP
IMP: 通过突变表型推断
22371574 MGI
acts upstream of or within regulation of glycogen metabolic process IMP
IMP: 通过突变表型推断
22371574 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
19365088 MGI
is active in cytosol IDA
IDA: 通过直接分析推断
26851500 MGI
located in nucleus IDA
IDA: 通过直接分析推断
19365088 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ketohexokinase

hepatic fructokinase

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-17613 Evocalcet Activator 99.28% 否
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P9925 Brodalumab Inhibitor 99.18% 否
HY-P9923 Benralizumab 99.1% 否
Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99955 Rocatinlimab 99.95% Phase 3
Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12841A KHK-IN-1 hydrochloride Inhibitor 98.47% 否
HY-103478 KHK-IN-2 Inhibitor 99.05% 否
HY-149987 LY3522348 Inhibitor 98.30% 否
HY-161993 BI-9787 Inhibitor 99.46% 否
HY-U00461 PF-06835919 Inhibitor 99.53% 否
HY-161993A (αR)-BI-9787 Inhibitor 98.63% 否
HY-12841 KHK-IN-1 Inhibitor 99.00% 否
HY-159123 KHK-6 Inhibitor / 否
HY-180921 GS-1291269 Inhibitor / 否
HY-RS07240 KHK Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-149605 KHK-IN-4 Inhibitor / 否
HY-162982 KHK-IN-6 / 否
HY-163886 KHK-IN-5 Inhibitor / 否
HY-172610 KHK-IN-7 Inhibitor / 否
HY-17613S Evocalcet-d4 Activator / 否
HY-RS17728 Khk Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24193 Khk Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991282 KHK2823 Inhibitor / 否
HY-P991536 KHK6640 Inhibitor / 否
HY-P991918 KHK2840 Agonist / 否
HY-P992004 KHK2805 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Khk NCBI NCBI:3795
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