2. Gene
  3. Alms1 - ALMS1, centrosome and basal body associated Gene

Alms1 - ALMS1, centrosome and basal body associated Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: bbb

基因 ID: 236266 | 基因类型: protein coding

关于 Alms1

功能概要

Enables alpha-actinin binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including Cholesterol homeostasis; gamete generation; and neuron development. Predicted to be active in centriole; centrosome; and cytosol. Is expressed in several structures, including aorta; central nervous system; genitourinary system; gut; and sensory organ. Used to study Alstrom syndrome and obesity. Human ortholog(s) of this gene implicated in Alstrom syndrome. Orthologous to human ALMS1 (ALMS1 centrosome and basal body associated protein). [provided by Alliance of Genome Resources, Apr 2022]

Alms1 基因产物(1)

mRNA Protein Name
NM_145223.2 NP_660258.2 centrosome-associated protein ALMS1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alpha-actinin binding IPI
IPI: 通过物理相互作用推断
22693585 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22693585 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of apoptotic process IMP
IMP: 通过突变表型推断
17206865 MGI
acts upstream of or within calcium-mediated signaling IMP
IMP: 通过突变表型推断
17206865 MGI
acts upstream of or within cholesterol homeostasis IMP
IMP: 通过突变表型推断
17206865 MGI
acts upstream of or within cilium assembly IMP
IMP: 通过突变表型推断
17206865 MGI
acts upstream of epithelial cell apoptotic process IMP
IMP: 通过突变表型推断
17206865 MGI
acts upstream of or within epithelial cell proliferation IMP
IMP: 通过突变表型推断
17206865 MGI
acts upstream of or within establishment of planar polarity IMP
IMP: 通过突变表型推断
21071598 MGI
acts upstream of or within glucose homeostasis IMP
IMP: 通过突变表型推断
16000322 MGI
acts upstream of or within inner ear receptor cell stereocilium organization IMP
IMP: 通过突变表型推断
21071598 MGI
acts upstream of or within lipid metabolic process IMP
IMP: 通过突变表型推断
16000322 MGI
acts upstream of or within negative regulation of epithelial cell apoptotic process IMP
IMP: 通过突变表型推断
17206865 MGI
acts upstream of or within negative regulation of multicellular organism growth IMP
IMP: 通过突变表型推断
16513793 MGI
acts upstream of or within ovulation IMP
IMP: 通过突变表型推断
16513793 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
27803297 MGI
acts upstream of or within regulation of fat cell differentiation IMP
IMP: 通过突变表型推断
16000322 MGI
acts upstream of or within retina development in camera-type eye IMP
IMP: 通过突变表型推断
31302159 MGI
acts upstream of or within retinal rod cell development IMP
IMP: 通过突变表型推断
16000322 MGI
acts upstream of or within sensory perception of sound IMP
IMP: 通过突变表型推断
16000322 MGI
acts upstream of or within spermatid development IMP
IMP: 通过突变表型推断
16513793 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

centrosome-associated protein ALMS1

Alstrom syndrome protein 1 homolog

Alstrom syndrome 1 homolog

alstrom syndrome protein 1 homolog

Alms1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Alms1 Q8K4E0 Actn4 Mus musculus P57780
Y2H
22693585
种属内
Alms1 Q8K4E0 Actn4 Mus musculus P57780
Anti Bait CoIP
22693585
种属内
Alms1 Q8K4E0 Actn1 Mus musculus Q7TPR4
Y2H
22693585
种属内
Alms1 Q8K4E0 Exosc8 Mus musculus Q9D753
Y2H
22693585
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00611 ALMS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22387 Alms1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28911 Alms1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Alms1 NCBI NCBI:7840
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