1. Gene
  2. Gstm1 - glutathione S-transferase mu 1 Gene

Gstm1 - glutathione S-transferase mu 1 Gene

种属: Rattus norvegicus

同用名: GSTA3

基因 ID: 24423 | 基因类型: protein coding

关于 Gstm1

功能概要

Enables several functions, including glutathione binding activity; glutathione transferase activity; and nickel cation binding activity. Involved in several processes, including response to ethanol; response to lead ion; and response to lithium ion. Located in cytosol and extracellular region. Part of protein-containing complex. Used to study cholestasis. Biomarker of hypertension and liver cirrhosis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system Cancer (multiple); hematologic Cancer (multiple); and lung disease (multiple). Orthologous to human GSTM1 (Glutathione S-transferase mu 1). [provided by Alliance of Genome Resources, Apr 2022]

Gstm1 基因产物(1)

mRNA Protein Name
NM_017014.2 NP_058710.2 glutathione S-transferase Mu 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glutathione binding IDA
IDA: 通过直接分析推断
17112229 RGD
enables glutathione transferase activity IDA
IDA: 通过直接分析推断
10229687 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
11015213 RGD
enables nickel cation binding IDA
IDA: 通过直接分析推断
7831282 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
23741294 RGD
enables steroid binding IPI
IPI: 通过物理相互作用推断
10229687 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in glutathione metabolic process IDA
IDA: 通过直接分析推断
10229687 RGD
involved in glutathione metabolic process IMP
IMP: 通过突变表型推断
12027896 RGD
involved in response to amino acid IEP
IEP: 通过表达模式推断
11040448 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
20298122 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
22545783 RGD
involved in response to lead ion IEP
IEP: 通过表达模式推断
9750042 RGD
involved in response to metal ion IEP
IEP: 通过表达模式推断
23470461 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
18754104 RGD
involved in xenobiotic catabolic process IDA
IDA: 通过直接分析推断
17112229 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
17112229 RGD
located in extracellular region IDA
IDA: 通过直接分析推断
10229687 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
11015213 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

glutathione S-transferase Mu 1

GST 3-3

GST Yb1

GSTM1-1

glutathione S-transferase M1

glutathione S-transferase Yb-1 subunit

glutathione-S-transferase, mu type 1 (Yb1)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gstm1 NCBI NCBI:2944