GRK5 - G protein-coupled receptor kinase 5 Gene

中文名称：G 蛋白偶联受体激酶 5

种属: Homo sapiens

同用名: GPRK5; FP2025

关于 GRK5

功能概要

该基因编码 Ser/Thr 蛋白激酶家族的鸟嘌呤核苷酸结合蛋白 (G 蛋白) 偶联受体激酶亚家族的成员。该蛋白质磷酸化 G 蛋白偶联受体的活化形式，从而启动它们的失活。它也被证明在调节多形核白细胞 (PMN) 的运动中发挥作用。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). [provided by RefSeq, Jul 2008]