2. GPCR/G Protein
  3. G Protein-coupled Receptor Kinase (GRK)
  4. GRL-03022

GRL-03022 是一种高效、选择性强的非共价 G 蛋白偶联受体激酶 5 (GRK5) 抑制剂，IC50 为 60 nM。GRL-03022 对 GRK2 的选择性比 GRK2 高 16000 倍以上 (IC50 > 1000 μM)。GRL-03022 可用于心力衰竭和癌症研究。

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GRL-03022

GRL-03022 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

GRL-03022 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GRL-03022 is a potent, selective and non-covalent G protein-coupled receptor kinase 5 (GRK5) inhibitor with an IC50 of 60 nM. GRL-03022 exhibits >16000-fold selectivity over GRK2 (IC50 > 1000 μM). GRL-03022 can be used for heart failure and cancer research[1].

IC50 & Target[1]

GRK2

>1000 μM (IC50)

GRK5

60 nM (IC50)

分子量

500.59

Formula

C29H32N4O4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

GRL-03022 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GRL-03022GRL03022GRL 03022G Protein-coupled Receptor Kinase (GRK)non-covalentG protein-coupled receptor kinase 5heart failureInhibitorinhibitorinhibit

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Inquiry Information

产品名称：
GRL-03022
目录号：
HY-179707
需求量：

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