ALG5 - ALG5 dolichyl-phosphate beta-glucosyltransferase Gene

中文名称：ALG5 多萜醇磷酸酯β-葡糖基转移酶

种属: Homo sapiens

同用名: PKD7; bA421P11.2

关于 ALG5

功能概要

该基因编码糖基转移酶 2 家族的一个成员。编码的蛋白质参与蛋白质 N-连接糖基化中寡聚甘露糖核心的糖基化。必须将葡萄糖残基添加到寡聚甘露糖核心以确保底物识别，并因此确保寡聚甘露糖核心有效转移到新生糖蛋白。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2008 年 11 月]

This gene encodes a member of the Glycosyltransferase 2 family. The encoded protein participates in glucosylation of the oligomannose core in N-linked glycosylation of proteins. The addition of glucose residues to the oligomannose core is necessary to ensure substrate recognition, and therefore, effectual transfer of the oligomannose core to the nascent glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]