2. Gene
  3. Nlrc5 - NLR family, CARD domain containing 5 Gene

Nlrc5 - NLR family, CARD domain containing 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NOD27

基因 ID: 434341 | 基因类型: protein coding

关于 Nlrc5

功能概要

Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in innate immune response; negative regulation of NF-kappaB transcription factor activity; and negative regulation of type I interferon-mediated signaling pathway. Acts upstream of or within response to bacterium. Located in cytosol and nucleus. Is expressed in liver. Orthologous to human NLRC5 (NLR family CARD domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]

Nlrc5 基因产物(1)

mRNA Protein Name
NM_001033207.3 NP_001028379.2 protein NLRC5
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in innate immune response IMP
IMP: 通过突变表型推断
20434986 MGI
involved in negative regulation of NF-kappaB transcription factor activity IDA
IDA: 通过直接分析推断
20434986 MGI
involved in negative regulation of type I interferon-mediated signaling pathway IDA
IDA: 通过直接分析推断
20434986 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
20639463 MGI
located in nucleus IDA
IDA: 通过直接分析推断
20639463 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein NLRC5

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09348 NLRC5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19724 Nlrc5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26220 Nlrc5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nlrc5 NCBI NCBI:84166
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