GPR179 - G protein-coupled receptor 179 Gene

中文名称：G 蛋白偶联受体 179

种属: Homo sapiens

同用名: CSNB1E; GPR158L; GPR158L1

基因 ID: 440435 | 基因类型: protein coding

关于 GPR179

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:38,324,571-38,343,956 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 196 orthologues, 1 paralogue and is associated with 3 phenotypes. Low expression observed in reference dataset.

功能概要

该基因编码 G 蛋白偶联受体的谷氨酸受体亚家族成员。所编码的蛋白质在蛋白质的 N 末端区域具有一个 EGF 样钙结合域和一个七个跨膜域。该基因的突变与 1E 型先天性静止性夜盲症有关。[RefSeq 提供，2012 年 4 月]

This gene encodes a member of the glutamate receptor subfamily of G protein-coupled receptors. The encoded protein has an EGF-like calcium binding domain and a seven transmembrane domain in the N-terminal region of the protein. Mutations in this gene are associated with congenital stationary night blindness type 1E. [provided by RefSeq, Apr 2012]

GPR179 基因产物(1)

mRNA	Protein	Name
NM_001004334.4	NP_001004334.3	probable G-protein coupled receptor 179 precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	30282023	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in visual perception	IMP IMP: 通过突变表型推断	22325362	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
is active in dendrite	IDA IDA: 通过直接分析推断	24084093	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GPR179 蛋白结构

7tm_3

0
400
800
1200
1600
2000
2367 a.a.

蛋白主名

其他名称

probable G-protein coupled receptor 179

GPR158-like 1

GPR179 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属间	GPR179	Q6PRD1	Egflam	Mus musculus	Q4VBE4	Pull Down	30282023
种属间	GPR179	Q6PRD1	Egflam	Mus musculus	Q4VBE4	Anti Tag CoIP	30282023
种属内	GPR179	Q6PRD1	EGFLAM	Homo sapiens	Q63HQ2	IF	30282023
种属内	GPR179	Q6PRD1	EGFLAM	Homo sapiens	Q63HQ2	Anti Tag CoIP	30282023
种属内	GPR179	Q6PRD1	GPC5	Homo sapiens	P78333	Anti Tag CoIP	30282023
种属内	GPR179	Q6PRD1	SDC4	Homo sapiens	P31431	Anti Tag CoIP	30282023
种属内	GPR179	Q6PRD1	GPC1	Homo sapiens	P35052	Anti Tag CoIP	30282023

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Night Blindness, Congenital Stationary, Type 1e

CSNB1E	Congenital Stationary Night Blindness 1e
Csnb, Complete, Autosomal Recessive	Night Blindness, Congenital Stationary , 1e, Autosomal Recessive
Congenital Stationary Night Blindness 1e Autosomal Recessive	Night Blindness, Congenital Stationary, 1e
Complete Autosomal Recessive Csnb	Csnb1
Night Blindness, Congenital Stationary, Type 1	Blindness, Night, Stationary, Congenital, Type 1e

Congenital Stationary Night Blindness

Night Blindness, Congenital Stationary	Congenital Essential Nyctalopia
Oguchi Disease	Blindness, Night, Stationary, Congenital

Fundus Dystrophy

Retinal Dystrophy	Retinal Dystrophies
Dystrophy, Retinal

Night Blindness

Nyctalopia

Abnormal Threshold Of Rods

Abnormal Dark Adaptation Curve

Night Blindness, Congenital Stationary, Type 1b

Congenital Stationary Night Blindness 1b	CSNB1B
Night Blindness, Congenital Stationary, Complete, Autosomal Recessive	Csnb, Complete, Autosomal Recessive
Night Blindness, Congenital Stationary , 1b, Autosomal Recessive	Autosomal Recessive Complete Congenital Stationary Night Blindness
Congenital Stationary Night Blindness 1b Autosomal Recessive	Night Blindness, Congenital Stationary, 1b
Complete Autosomal Recessive Csnb	Complete Congenital Stationary Night Blindness Autosomal Recessive
Blindness, Night, Stationary, Congenital, Type 1b

Cone-Rod Dystrophy 15

Retinitis Pigmentosa 65	CORD15
Dystrophy, Cone-Rod, Type 15

Night Blindness, Congenital Stationary, Type 1c

Congenital Stationary Night Blindness 1c	CSNB1C
Csnb, Complete, Autosomal Recessive	Night Blindness, Congenital Stationary , 1c, Autosomal Recessive
Congenital Stationary Night Blindness 1c Autosomal Recessive	Night Blindness, Congenital Stationary, 1c
Complete Autosomal Recessive Csnb	Night Blindness, Congenital Stationary, Type Ic
Blindness, Night, Stationary, Congenital, Type 1c

Night Blindness, Congenital Stationary, Type 1a

Congenital Stationary Night Blindness 1a	CSNB1A
Hemeralopia-Myopia	Myopia-Night Blindness
Night Blindness, Congenital Stationary , 1a, X-Linked	Congenital Stationary Night Blindness With Myopia
Csnb, Complete, X-Linked	Night Blindness, Congenital Stationary, With Myopia
Nbm1	Complete Csnb X-Linked
Congenital Stationary Night Blindness 1a X-Linked	Nbmi
Night Blindness, Congenital Stationary, 1a	Complete X-Linked Csnb
Nyctalopia	Xlcsnb
X-Linked Congenital Stationary Night Blindness	Blindness, Night, Stationary, Congenital, Type 1a
Night Blindness	X-Linked Csnb
Night Blindness, Congenital Stationary, Type 2a

Retinitis Pigmentosa 86

RP86	Retinitis Pigmentosa, Type 86

Fundus Albipunctatus

Retinitis Punctata Albescens	Pigmentary Retinal Dystrophy
RPA	Albipunctate Retinal Dystrophy
Lauber'S Disease	FALBI
Fa

Refractive Error

Refractive Errors

Leber Plus Disease

Leber Congenital Amaurosis	Lca
Leber'S Amaurosis	Leber'S Disease
Amaurosis Congenita Of Leber	Amaurosis Congenita Of Leber, Type 1
Lhon Plus Disease	Congenital Absence Of The Rods And Cones
Congenital Retinal Blindness	Crb
Congenital Amaurosis Of Retinal Origin	Leber'S Congenital Amaurosis
Leber Congenital Amaurosis 1	Leber'S Congenital Tapetoretinal Degeneration
Leber'S Congenital Tapetoretinal Dysplasia	Lca1
Leber Congenital Amaurosis Type 1	Retinal Blindness, Congenital
Amaurosis, Leber Congenital	Dysgenesis Neuroepithelialis Retinae
Hereditary Epithelial Dysplasia Of Retina	Hereditary Retinal Aplasia
Heredoretinopathia Congenitalis	Leber Abiotrophy
Leber Congenital Tapetoretinal Degeneration	Lebers Congenital Amaurosis
Optic Atrophy, Hereditary, Leber

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS05686	GPR179 Human Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	GPR179	MGD	MGI:2443409
Felis catus	GPR179	VGNC	VGNC:62689
Macaca mulatta	GPR179	VGNC	VGNC:73043
Bos taurus	GPR179	VGNC	VGNC:29573
Rattus norvegicus	GPR179	RGD	RGD:1560033
Canis familiaris	GPR179	VGNC	VGNC:41419

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

粤ICP备2021105330号-3

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

GPR179 - G protein-coupled receptor 179 Gene

关于 GPR179

功能概要

GPR179 基因产物(1)

GPR179 蛋白结构

GPR179 蛋白互作信息

关联疾病

直系同源

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GPR179 - G protein-coupled receptor 179 Gene

关于 GPR179

功能概要

GPR179 基因产物(1)

GPR179 蛋白结构

GPR179 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z