2. Gene
  3. ERMN - ermin Gene

ERMN - ermin Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：害虫

种属: Homo sapiens

同用名: JN; KIAA1189

基因 ID: 57471 | 基因类型: protein coding

关于 ERMN

Cytogenetic location: 2q24.1 Genomic coordinates (GRCh38): 2:157,318,631-157,327,712 (from NCBI)

This gene has 9 transcripts (splice variants), 106 orthologues and 6 paralogues. Restricted expression toward brain (RPKM 77.3).

功能概要

预测启用肌动蛋白丝结合活性。参与肌动蛋白丝组织；细胞投射组织的调节；和细胞形状的调节。位于细胞皮层；轴突的节间区域；和轴突的副节点区域。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable actin filament binding activity. Involved in actin filament organization; regulation of cell projection organization; and regulation of cell shape. Located in cell cortex; internode region of axon; and paranode region of axon. [provided by Alliance of Genome Resources, Apr 2022]

ERMN 基因产物(5)

mRNA Protein Name
NM_001009959.3 NP_001009959.1 ermin isoform a
NM_001304344.2 NP_001291273.1 ermin isoform b
NM_001304345.2 NP_001291274.1 ermin isoform b
NM_001304346.2 NP_001291275.1 ermin isoform c
NM_020711.3 NP_065762.1 ermin isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin filament organization IDA
IDA: 通过直接分析推断
20934411 GOA
involved in regulation of cell projection organization IDA
IDA: 通过直接分析推断
20934411 GOA
involved in regulation of cell shape IDA
IDA: 通过直接分析推断
20934411 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell cortex IDA
IDA: 通过直接分析推断
20934411 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
20934411 GOA
located in internode region of axon IDA
IDA: 通过直接分析推断
20934411 GOA
located in paranode region of axon IDA
IDA: 通过直接分析推断
20934411 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ermin

ermin, ERM-like protein

ERMN 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ERMN Q8TAM6 RTN4IP1 Homo sapiens Q8WWV3
Validated Y2H
32296183
种属内
ERMN Q8TAM6 RTN4IP1 Homo sapiens Q8WWV3
Y2H Prey Pooling
32296183
种属内
ERMN Q8TAM6 RTN4IP1 Homo sapiens Q8WWV3
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Developmental And Epileptic Encephalopathy 84

DEE84

Jamuar Syndrome

Eiee84

Developmental And Epileptic Encephalopathy, 84

Epileptic Encephalopathy, Early Ifantile, 84

Early Infantile Epileptic Encephalopathy 84

Epileptic Encephalopathy, Early Infantile, 84

Encephalopathy, Epileptic, Early Infantile, Type 84
Atrial Septal Defect 5

ASD5

Atrial Heart Septal Defect 5

Septal Defect, Atrial, Type 5
Developmental And Epileptic Encephalopathy 28

DEE28

Epileptic Encephalopathy, Early Infantile, 28

Eiee28

Developmental And Epileptic Encephalopathy, 28

Early Infantile Epileptic Encephalopathy 28

Encephalopathy, Epileptic, Early Infantile, Type 28
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04505 ERMN Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ERMN MGD MGI:1925017
Canis familiaris ERMN VGNC VGNC:40462
Felis catus ERMN VGNC VGNC:80202
Rattus norvegicus ERMN RGD RGD:1308367
Macaca mulatta ERMN VGNC VGNC:99360
Bos taurus ERMN VGNC VGNC:28591
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