2. Gene
  3. Wdr4 - WD repeat domain 4 Gene

Wdr4 - WD repeat domain 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Wh; mWH; D530049K22Rik

基因 ID: 57773 | 基因类型: protein coding

关于 Wdr4

功能概要

Predicted to contribute to tRNA (guanine-N7-)-methyltransferase activity. Predicted to be involved in tRNA modification. Predicted to act upstream of or within cellular response to DNA damage stimulus and tRNA processing. Predicted to be located in nucleoplasm. Predicted to be part of tRNA methyltransferase complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and thymus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome. Orthologous to human WDR4 (WD repeat domain 4). [provided by Alliance of Genome Resources, Apr 2022]

Wdr4 基因产物(6)

mRNA Protein Name
NM_001405110.1 NP_001392039.1 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 isoform b precursor
NM_001405114.1 NP_001392043.1 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 isoform c
NM_001405117.1 NP_001392046.1 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 isoform c
NM_001405119.1 NP_001392048.1 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 isoform c
NM_001405120.1 NP_001392049.1 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 isoform c
NM_021322.3 NP_067297.2 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
36681682 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4

WD repeat-containing protein 4

WD40 repeat protein 4

protein Wuho homolog

tRNA (guanine-N(7)-)-methyltransferase subunit WDR4

Wdr4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Wdr4 Q9EP82 Arhgap17 Mus musculus Q3UIA2
Anti Tag CoIP
36681682
种属内
Wdr4 Q9EP82 Arhgap17 Mus musculus Q3UIA2
Anti Bait CoIP
36681682
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-162080 METTL1-WDR4-IN-1 Inhibitor 99.61% 否
HY-162082 METTL1-WDR4-IN-2 Inhibitor 99.71% 否
HY-162080A METTL1-WDR4-IN-1 TFA Inhibitor 99.61% 否
HY-RS15777 WDR4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22359 Wdr4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28881 Wdr4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Wdr4 NCBI NCBI:10785
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