1. Gene
  2. Bcor - BCL6 interacting corepressor Gene

Bcor - BCL6 interacting corepressor Gene

种属: Mus musculus

同用名: BcorR; mKIAA1575; 2900008C10Rik; 5830466J11Rik; 8430401K06Rik; D930024N20Rik

基因 ID: 71458 | 基因类型: protein coding

关于 Bcor

功能概要

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and transcription corepressor activity. Acts upstream of or within blastocyst hatching and negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; gonad; and lung. Human ortholog(s) of this gene implicated in colorectal cancer; stomach cancer; stomach carcinoma; syndromic microphthalmia 1; and syndromic microphthalmia 2. Orthologous to human BCOR (BCL6 corepressor). [provided by Alliance of Genome Resources, Apr 2022]

Bcor 基因产物(5)

mRNA Protein Name
NM_001168321.1 NP_001161793.1 BCL-6 corepressor isoform d
NM_029510.3 NP_083786.2 BCL-6 corepressor isoform a
NM_175044.3 NP_778209.2 BCL-6 corepressor isoform b
NM_175045.3 NP_778210.2 BCL-6 corepressor isoform c
NM_175046.3 NP_778211.2 BCL-6 corepressor isoform d
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
25331958 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12522145 MGI
enables transcription corepressor activity IPI
IPI: 通过物理相互作用推断
12776190 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blastocyst hatching IMP
IMP: 通过突变表型推断
27869233 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12776190 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
25331958 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12776190 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

BCL-6 corepressor

Bcor 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Bcor Q8CGN4 Bcl6 Mus musculus P41183 25490446
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bcor NCBI NCBI:54880