1. Gene
  2. Cblc - Casitas B-lineage lymphoma c Gene

Cblc - Casitas B-lineage lymphoma c Gene

种属: Mus musculus

同用名: Cbl3; 2310076I21Rik; 2310079L19Rik

基因 ID: 80794 | 基因类型: protein coding

关于 Cblc

功能概要

Predicted to enable several functions, including SH3 domain binding activity; phosphotyrosine residue binding activity; and signaling receptor binding activity. Predicted to be involved in cellular protein metabolic process; negative regulation of protein kinase activity; and signal transduction. Predicted to be part of ubiquitin Ligase complex. Predicted to be active in membrane raft and plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; lung; and sensory organ. Orthologous to human CBLC (Cbl proto-oncogene C). [provided by Alliance of Genome Resources, Apr 2022]

Cblc 基因产物(2)

mRNA Protein Name
NM_001161844.1 NP_001155316.1 E3 ubiquitin-protein ligase CBL-C isoform 2
NM_023224.5 NP_075713.3 E3 ubiquitin-protein ligase CBL-C isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18753381 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of neuron apoptotic process IDA
IDA: 通过直接分析推断
18753381 MGI
acts upstream of or within protein catabolic process IDA
IDA: 通过直接分析推断
18753381 MGI
acts upstream of or within protein stabilization IDA
IDA: 通过直接分析推断
18753381 MGI
acts upstream of or within response to glial cell derived neurotrophic factor IDA
IDA: 通过直接分析推断
18753381 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase CBL-C

CBL-3

RING-type E3 ubiquitin transferase CBL-C

SH3-binding protein CBL-3

SH3-binding protein CBL-C

signal transduction protein CBL-C

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cblc NCBI NCBI:23624