2. Gene
  3. Atf2 - activating transcription factor 2 Gene

Atf2 - activating transcription factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 81647 | 基因类型: protein coding

关于 Atf2

功能概要

Enables cAMP response element binding activity. Involved in several processes, including amelogenesis; positive regulation of neuron apoptotic process; and regulation of transcription by RNA polymerase II. Located in nucleus. Used to study hypertension and transient cerebral ischemia. Biomarker of glaucoma and transient cerebral ischemia. Orthologous to human ATF2 (activating transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Atf2 基因产物(2)

mRNA Protein Name
NM_031018.2 NP_112280.1 cyclic AMP-dependent transcription factor ATF-2
NM_031018.2 NP_112280.1 cyclic AMP-dependent transcription factor ATF-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cAMP response element binding IDA
IDA: 通过直接分析推断
12196528 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
17428807 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
17428807 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in amelogenesis IDA
IDA: 通过直接分析推断
15218628 RGD
involved in negative regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
20181929 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
20181929 RGD
involved in positive regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
19255142 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12453892 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of CCAAT-binding factor complex IDA
IDA: 通过直接分析推断
8703044 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cyclic AMP-dependent transcription factor ATF-2

cAMP response element-binding protein CRE-BP1

cAMP-dependent transcription factor ATF-2

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B1198 Piperonyl butoxide Inhibitor 98.0% 否
HY-B1198R Piperonyl butoxide (Standard) Inhibitor / 否
Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-13241 Ralimetinib dimesylate 99.97% Phase 2
HY-13241A Ralimetinib Inhibitor 98.58% Phase 2
Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-152860 Darizmetinib 99.94% 否
HY-134963 SBI-0087702 99.55% 否
HY-117987 CPS-11 99.39% 否
HY-RS01128 ATF2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-B1198S Piperonyl butoxide-d9 Inhibitor / 否
HY-180419 SF-3-030 / 否
HY-RS05361 GDNF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17003 Atf2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23446 Atf2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W585976 Benzo[a]pyrene diol epoxide / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atf2 NCBI NCBI:1386
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