2. Gene
  3. Pde1c - phosphodiesterase 1C Gene

Pde1c - phosphodiesterase 1C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 81742 | 基因类型: protein coding

关于 Pde1c

功能概要

Enables cAMP binding activity; calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; and calmodulin-dependent cyclic-nucleotide phosphodiesterase activity. Involved in negative regulation of Insulin secretion involved in cellular response to glucose stimulus and sensory perception of smell. Acts upstream of or within response to calcium ion. Located in neuronal cell body. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 74. Orthologous to human PDE1C (phosphodiesterase 1C). [provided by Alliance of Genome Resources, Apr 2022]

Pde1c 基因产物(1)

mRNA Protein Name
NM_031078.2 NP_112340.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cAMP binding IDA
IDA: 通过直接分析推断
7568196 RGD
enables calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity IDA
IDA: 通过直接分析推断
7568196 RGD
enables calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity IDA
IDA: 通过直接分析推断
7568196 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
18706893 RGD
acts upstream of or within response to calcium ion IDA
IDA: 通过直接分析推断
7568196 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in neuronal cell body IDA
IDA: 通过直接分析推断
16881052 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C

calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C

3',5'-cyclic-AMP phosphodiesterase

3',5'-cyclic-GMP phosphodiesterase

cam-PDE 1C

cyclic nucleotide phosphodiesterase 1 C

dual specificity Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C

phosphodiesterase 1C calmodulin-depend

相关产品

Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-12501A ITI-214 Inhibitor 99.19% Phase 2
HY-112831 Osoresnontrine Inhibitor 99.88% Phase 2
HY-12501 ITI-214 free base Inhibitor 98.0% Phase 2
Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101490 PDE1-IN-2 Inhibitor 98.0% 否
HY-169402 PDE1-IN-9 Inhibitor / 否
HY-169402A PDE1-IN-9 hydrochloride Inhibitor / 否
HY-120741 PF-04822163 Inhibitor / 否
HY-120195 PF-04677490 Inhibitor / 否
HY-120195A PF-04827736 Inhibitor / 否
HY-147946 PDE1-IN-4 Inhibitor / 否
HY-155199 PDE1-IN-5 Inhibitor / 否
HY-RS10212 PDE1C Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19228 Pde1c Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25717 Pde1c Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-U00374 Sch59498 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pde1c NCBI NCBI:5137
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