1. Gene
  2. MEX3B - mex-3 RNA binding family member B Gene

MEX3B - mex-3 RNA binding family member B Gene

中文名称:mex-3 RNA 结合家族成员 B

种属: Homo sapiens

同用名: RKHD3; MEX-3B; RNF195

基因 ID: 84206 | 基因类型: protein coding

关于 MEX3B

Cytogenetic location: 15q25.2 Genomic coordinates (GRCh38): 15:82,041,778-82,046,018 (from NCBI)

This gene has 2 transcripts (splice variants), 189 orthologues and 3 paralogues. Biased expression in testis (RPKM 20.7), endometrium (RPKM 5.5) and 7 other tissues.

功能概要

该基因编码一种 RNA 结合磷蛋白,它是 MEX3 (肌肉过剩 3) 翻译调节因子家族的一部分。编码的蛋白质包含 N 端核输出和核定位信号,并从细胞质输出到细胞核。该蛋白质通过两个 KH 结构域与 RNA 结合,还与 P (加工) 体内的 MEX3A、Dcp1A 脱帽因子和 Argonaute 蛋白共定位。[RefSeq 提供,2012 年 10 月]

This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies. [provided by RefSeq, Oct 2012]

MEX3B 基因产物(1)

mRNA Protein Name
NM_032246.6 NP_115622.2 RNA-binding protein MEX3B

MEX3B 蛋白结构

KH_1

KH_1: KH domain (68 - 127)

KH_1

KH_1: KH domain (162 - 221)

zf-C3HC4_3

zf-C3HC4_3: Zinc finger, C3HC4 type (RING finger) (516 - 563)

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  • 569 a.a.
蛋白主名 其他名称

RNA-binding protein MEX3B

RING finger protein 195

MEX3B 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MEX3B Q6ZN04 YWHAE Homo sapiens P62258 36931259
种属间: 跨种属相互作用 种属内: 同种属相互作用

MEX3B 抗体

目录号 产品名 应用 反应物种
HY-P810200 Mex3b Antibody (YA9544) WB, IP, ELISA human, mouse, rat

直系同源

种属 基因名 来源 基因 ID
Mus musculus MEX3B MGD MGI:1918252
Bos taurus MEX3B VGNC VGNC:54452
Felis catus MEX3B VGNC VGNC:80912
Rattus norvegicus MEX3B RGD RGD:1306790
Canis familiaris MEX3B VGNC VGNC:43184
Macaca mulatta MEX3B VGNC VGNC:74574