2. Gene
  3. ADTRP - androgen dependent TFPI regulating protein Gene

ADTRP - androgen dependent TFPI regulating protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：雄激素依赖性 TFPI 调节蛋白

种属: Homo sapiens

同用名: AIG1L; C6orf105; dJ413H6.1

基因 ID: 84830 | 基因类型: protein coding

关于 ADTRP

Cytogenetic location: 6p24.1 Genomic coordinates (GRCh38): 6:11,713,523-11,778,803 (from NCBI)

This gene has 10 transcripts (splice variants), 199 orthologues and 1 paralogue. Biased expression in small intestine (RPKM 12.0), duodenum (RPKM 8.7) and 8 other tissues.

功能概要

启用水解酶活性。参与多个过程，包括参与新血管生成的细胞迁移；细胞分泌的负调节；和大分子代谢过程的正向调控。位于小窝和细胞表面。 [由基因组资源联盟提供，2022 年 4 月]

Enables hydrolase activity. Involved in several processes, including cell migration involved in sprouting angiogenesis; negative regulation of secretion by cell; and positive regulation of macromolecule metabolic process. Located in caveola and cell surface. [provided by Alliance of Genome Resources, Apr 2022]

ADTRP 基因产物(2)

mRNA Protein Name
NM_001143948.2 NP_001137420.1 androgen-dependent TFPI-regulating protein isoform 1
NM_032744.4 NP_116133.1 androgen-dependent TFPI-regulating protein isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hydrolase activity IMP
IMP: 通过突变表型推断
27018888 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell migration involved in sprouting angiogenesis IMP
IMP: 通过突变表型推断
28341552 GOA
involved in cellular response to oxidised low-density lipoprotein particle stimulus IMP
IMP: 通过突变表型推断
28341552 GOA
involved in cellular response to steroid hormone stimulus IEP
IEP: 通过表达模式推断
21868574 GOA
involved in long-chain fatty acid catabolic process IMP
IMP: 通过突变表型推断
27018888 GOA
involved in negative regulation of blood coagulation IMP
IMP: 通过突变表型推断
21868574 GOA
involved in negative regulation of extracellular matrix constituent secretion IMP
IMP: 通过突变表型推断
28341552 GOA
involved in negative regulation of leukocyte cell-cell adhesion IMP
IMP: 通过突变表型推断
28341552 GOA
involved in negative regulation of leukocyte migration IMP
IMP: 通过突变表型推断
28341552 GOA
involved in negative regulation of lymphocyte migration IMP
IMP: 通过突变表型推断
28341552 GOA
involved in negative regulation of protein secretion IMP
IMP: 通过突变表型推断
28341552 GOA
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
21868574 GOA
involved in positive regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
28341552 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in caveola IDA
IDA: 通过直接分析推断
21868574 GOA
located in cell surface IDA
IDA: 通过直接分析推断
21868574 GOA
located in membrane IDA
IDA: 通过直接分析推断
27018888 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ADTRP 蛋白结构

Far-17a_AIG1

Far-17a_AIG1: FAR-17a/AIG1-like protein (6 - 216)

  • 0
  • 100
  • 200
  • 230 a.a.
蛋白主名 其他名称

androgen-dependent TFPI-regulating protein

FAHFA hydrolase ADTRP

关联疾病

疾病名称 别名
Nonobstructive Coronary Artery Disease

Non-Cad

Non-Obstructive Coronary Artery Disease
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P11655 NOTA-TATE Ligand / 否
HY-RS00421 ADTRP Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ADTRP VGNC VGNC:37680
Felis catus ADTRP VGNC VGNC:102376
Mus musculus ADTRP MGD MGI:1924596
Rattus norvegicus ADTRP RGD RGD:1305679
Macaca mulatta ADTRP VGNC VGNC:69661
Bos taurus ADTRP VGNC VGNC:25702
Others ADTRP NCBI
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