2. Gene
  3. Trpc6 - transient receptor potential cation channel, subfamily C, member 6 Gene

Trpc6 - transient receptor potential cation channel, subfamily C, member 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Trrp6

基因 ID: 89823 | 基因类型: protein coding

关于 Trpc6

功能概要

Enables several functions, including ATPase binding activity; clathrin binding activity; and cytoskeletal protein binding activity. Involved in several processes, including cellular response to hydrogen peroxide; generation of neurons; and positive regulation of peptidyl-threonine phosphorylation. Located in plasma membrane. Used to study focal segmental glomerulosclerosis; kidney disease; and transient cerebral ischemia. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in chronic fatigue syndrome; focal segmental glomerulosclerosis; focal segmental glomerulosclerosis 2; and nephrotic syndrome type 2. Orthologous to human TRPC6 (transient receptor potential cation channel subfamily C member 6). [provided by Alliance of Genome Resources, Apr 2022]

Trpc6 基因产物(1)

mRNA Protein Name
NM_053559.1 NP_446011.1 short transient receptor potential channel 6
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATPase binding IPI
IPI: 通过物理相互作用推断
16025302 RGD
enables actin binding IDA
IDA: 通过直接分析推断
16025302 RGD
enables actinin binding IDA
IDA: 通过直接分析推断
16025302 RGD
enables calcium channel activity IDA
IDA: 通过直接分析推断
20501650 RGD
enables clathrin binding IDA
IDA: 通过直接分析推断
16025302 RGD
enables monoatomic cation channel activity IDA
IDA: 通过直接分析推断
11278449 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16025302 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hydrogen peroxide IDA
IDA: 通过直接分析推断
20501650 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
19889962 RGD
involved in negative regulation of dendrite morphogenesis IMP
IMP: 通过突变表型推断
22764246 RGD
involved in neuron differentiation IEP
IEP: 通过表达模式推断
20479868 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
11788346 RGD
involved in positive regulation of cytosolic calcium ion concentration IMP
IMP: 通过突变表型推断
22764246 RGD
involved in positive regulation of neuron differentiation IMP
IMP: 通过突变表型推断
20479868 RGD
involved in positive regulation of peptidyl-threonine phosphorylation IMP
IMP: 通过突变表型推断
22699894 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

short transient receptor potential channel 6

transient receptor protein 6

相关产品

Pre-clinical Phase
生物活性分子 (32)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-111925 BI-749327 Antagonist 99.91% 否
HY-116330A Hyperforin dicyclohexylammonium salt 99.48% 否
HY-111098 GSK1702934A Agonist 99.11% 否
HY-101507 Zerencotrep Inhibitor 99.47% 否
HY-12949 ML204 Inhibitor 98.45% 否
HY-108457 9-Phenanthrol Inhibitor 99.61% 否
HY-15699 SAR7334 Inhibitor 99.21% 否
HY-122051 AC1903 Inhibitor 99.80% 否
HY-101795 Larixyl acetate Inhibitor 99.44% 否
HY-15699A SAR7334 hydrochloride Inhibitor 98.0% 否
HY-148129 Apecotrep Inhibitor 99.17% 否
HY-N10756 Hyp9 Agonist 99.90% 否
HY-12949A ML204 hydrochloride Inhibitor 99.74% 否
HY-136190 TRPC6-PAM-C20 Agonist 99.78% 否
HY-133012 GFB-8438 Inhibitor 99.74% 否
HY-111527 PPZ2 99.92% 否
HY-W744699 Larixol Inhibitor 95.52% 否
HY-101547 TRPC6-IN-1 Inhibitor 99.71% 否
HY-RS16595 Trpc6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-116330 Hyperforin / 否
HY-120818 TRPC3/6-IN-3 / 否
HY-121519 GSK2332255B Antagonist / 否
HY-145151 TRPC6-IN-2 / 否
HY-147357 TRPC3/6-IN-1 Inhibitor / 否
HY-153455 TRPC3/6-IN-2 Inhibitor / 否
HY-172600 TRPC6 antagonist-1 Antagonist / 否
HY-179490 AM-0883 Agonist / 否
HY-RS15109 TRPC6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W707161 4-Methyl-2-(1-piperidinyl)-quinoline-d10 / 否
HY-W745090 Isomaltulose monohydrate / 否
HY-RS23029 Trpc6 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-112298 DS88790512 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trpc6 NCBI NCBI:7225
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