1. Metabolic Enzyme/Protease
  2. MetAP
  3. JNJ-4929821

JNJ-4929821 (Compound 88) 是一种三唑衍生物,是一种选择性甲硫氨酸氨肽酶-2 (MetAP-2) 抑制剂,对 MetAP-2 的 IC50 为 15 nM,优于对 MetAP-1 的抑制效力。JNJ-4929821 可用于肝癌、结直肠腺癌和胰腺癌等癌症的研究。

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JNJ-4929821

JNJ-4929821 Chemical Structure

CAS No. : 836671-12-6

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查看 MetAP 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

JNJ-4929821 (Compound 88), a triazole derivative, is a selective Methionine aminopeptidase-2 (MetAP-2) inhibitor with an IC50 of 15  nM over MetAP-1. JNJ-4929821 can be used for cancers like liver cancer, colorectal adenocarcinoma and pancreatic cancer research[1].

IC50 & Target[1]

MetAp2

15 nM (IC50)

分子量

352.41

Formula

C14H13FN4O2S2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
JNJ-4929821
目录号:
HY-122225
需求量: