2. Anti-infection Metabolic Enzyme/Protease Immunology/Inflammation NF-κB
  3. Bacterial Reactive Oxygen Species (ROS)
  4. (K(C10)GGGRrRPC)2

(K(C10)GGGRrRPC)2 (Compound (C-C10)C-C) 是一种二聚体脂肽和抗菌 (antibacterial) 剂。(K(C10)GGGRrRPC)2 可增强活性氧 (ROS) 的积累，并抑制细菌呼吸链脱氢酶 (respiratory chain dehydrogenase) 的活性。(K(C10)GGGRrRPC)2 可显著抑制细菌生物膜的形成。(K(C10)GGGRrRPC)2 对鲍曼不动杆菌 AB1901、鲍曼不动杆菌 AB1902、铜绿假单胞菌 25349 和金黄色葡萄球菌 11011 均具有抗菌活性，其 MIC 分别为 4 μM、8 μM、4 μM 和 8 μM。(K(C10)GGGRrRPC)2 对大肠杆菌 ATCC 25922 也显示出抗菌效果。

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Custom Peptide Synthesis

(K(C10)GGGRrRPC)2

(K(C10)GGGRrRPC)2 Chemical Structure

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(K(C10)GGGRrRPC)2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(K(C10)GGGRrRPC)2 (Compound (C-C10)C-C) is a dimeric lipopeptide and antibacterial agent. (K(C10)GGGRrRPC)2 enhances the accumulation of ROS, inhibits the bacterial respiratory chain dehydrogenase activity. (K(C10)GGGRrRPC)2 exhibits significant inhibition of bacterial biofilm formation. (K(C10)GGGRrRPC)2 exhibits antimicrobial activity against Acinetobacter baumannii AB1901, A. baumannii AB1902, Pseudomonas aeruginosa 25349, Staphylococcus aureus 11011, with MICs of 4 μM, 8 μM, 4 μM, and 8 μM, respectively. (K(C10)GGGRrRPC)2 shows antimicrobial efficacy against E. coli ATCC 25922[1].

分子量

2278.80

Formula

C96H176N38O22S2
Sequence

{Lys(decanal)}-Gly-Gly-Gly-Arg-{d-Arg}-Arg-Pro-Cys-Cys-Pro-Arg-{d-Arg}-Arg-Gly-Gly-Gly-{Lys(decanal)} (Disulfide bridge: Cys9-Cys10)
Sequence Shortening

{Lys(decanal)}-GGGR-{d-Arg}-RRPCCPRR-{d-Arg}-RGGG-{Lys(decanal)} (Disulfide bridge: Cys9-Cys10)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(K(C10)GGGRrRPC)2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(K(C10)GGGRrRPC)2BacterialReactive Oxygen Species (ROS)Inhibitorinhibitorinhibit

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