1. Protein Tyrosine Kinase/RTK Immunology/Inflammation
  2. Src Interleukin Related
  3. Lck-IN-6

Lck-IN-6 (Compound 12g) 是一种 Lck 抑制剂,IC50 为 3 nM。Lck-IN-6 可抑制 IL-2 的产生。Lck-IN-6 可用于类风湿性关节炎、炎症性肠病研究。

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Lck-IN-6

Lck-IN-6 Chemical Structure

CAS No. : 918870-43-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lck-IN-6 (Compound 12g) is a Lck inhibitor with an IC50 of 3 nM. Lck-IN-6 inhibits the production of IL-2. Lck-IN-6 can be used in the research of rheumatoid arthritis and inflammatory bowel disease[1].

IC50 & Target[1]

Lck

3 nM (IC50)

体外研究
(In Vitro)

Lck-IN-6 可抑制重组人源活性 Lck,其 IC50 为 3 nM[1]
Lck-IN-6 可抑制受刺激的 Jurkat E6-1 人急性 T 细胞白血病细胞中 IL-2 的产生,其 IC50 为 0.054 μM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

446.51

Formula

C24H26N6O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Lck-IN-6
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HY-112448
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