XMD8-92 and JWG-045 exhibit anti-ferroptotic activities, independently of inhibiting ERK5

Affiliations

• 1 Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health (FBMH), University of Manchester, Michael Smith Building, Oxford Road, Manchester, M13 9PT, UK.
• 2 Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.
• 3 Division of Pharmacy and Optometry, School of Health Sciences, FBMH, University of Manchester, Manchester, UK.
• 4 Institute of Biomedicine, University of Turku, Turku, 20520, Finland.
• 5 Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
• 6 Division of Molecular and Cellular Function, School of Biological Sciences, FBMH, University of Manchester, Manchester, UK.
• 7 Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health (FBMH), University of Manchester, Michael Smith Building, Oxford Road, Manchester, M13 9PT, UK. cathy.tournier@manchester.ac.uk.