2. Anti-infection
  3. Fungal
  4. Metconazole

Metconazole 是一种 14α-脱甲基化抑制剂 (DMI) 类杀菌剂。Metconazole 可抑制真菌麦角甾醇生物合成、菌丝体生长及分生孢子芽管伸长。Metconazole 会降低抗氧化酶活性。Metconazole 可减少小麦镰刀菌冠腐病的发生。

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Metconazole

Metconazole Chemical Structure

CAS No. : 125116-23-6

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规格 价格 是否有货 数量
100 mg ￥180
In-stock
250 mg ￥306
In-stock
500 mg ￥475
In-stock
1 g ￥760
询价
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Other Forms of Metconazole:

Metconazole 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Metconazole is a 14α-demethylation inhibitor (DMI) fungicide. Metconazole inhibits fungal ergosterol biosynthesis, inhibits mycelial growth and conidial germ tube elongation. Metconazole reduces antioxidant enzyme activities. Metconazole reduces occurrence of Fusarium crown rot in wheat[1].

体外研究
(In Vitro)

Metconazole (0.001-0.1 μg/mL; 3 days) 可强效抑制 39 株假禾谷镰孢菌 (Fusarium pseudograminearum) 的菌丝生长，平均 EC50 值为 0.019 μg/mL[1]。
Metconazole (0.05-0.2 μg/mL; 6-12 h) 可抑制 39 株假禾谷镰孢菌的分生孢子形成、萌发及芽管伸长[1]。
Metconazole (0.02-0.2 μg/mL; 6 h) 可在假禾谷镰孢菌株 PY20-16 中诱导显著的转录水平变化，包括上调麦角固醇生物合成基因和 9 个 ABC 转运蛋白基因[1]。
Metconazole (0.002-0.2 μg/mL; 7 days) 在 0.02 μg/mL 和 0.2 μg/mL 浓度下可抑制 Fusarium pseudograminearum 菌株 CF1494 和 PY20-16 中 DON、15-ADON 及 ZEN 的产生，而 0.002 μg/mL 浓度下可促进 DON 和 15-ADON 的产生，但仍能抑制 ZEN 的产生[1]。
Metconazole (0.05-0.2 μg/mL; 12 h) 可呈剂量依赖性显著降低假禾谷镰孢菌菌株 PY20-16 中的麦角固醇生成量[1]。
Metconazole (0.05-0.2 μg/mL) 可显著降低假禾谷镰孢菌菌丝体中过氧化氢酶与过氧化物酶的活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Metconazole 相关抗体:
体内研究
(In Vivo)

Metconazole (按种子重量计 0.06-0.14 μl AI/g，种子处理) 在温室条件下对小麦镰孢菌茎基腐病可达到 32.79-77.24% 的防效[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Seeds (Jimai 19)[1]
Dosage: 0.06 μl AI/g seeds; 0.1 μl AI/g seeds; 0.14 μl AI/g seeds
Administration: seed treatment
Result: Achieved 32.79% control efficacy against Fusarium crown rot at 0.06 μl AI/g seeds.
Achieved 59.16% control efficacy against Fusarium crown rot at 0.1 μl AI/g seeds.
Achieved 77.24% control efficacy against Fusarium crown rot at 0.14 μl AI/g seeds.
Significantly reduced disease occurrence.
分子量

319.83

Formula

C17H22ClN3O
CAS 号
非标记 CAS
性状

固体

中文名称

叶菌唑
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
纯度 & 产品资料
参考文献

Metconazole 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Metconazole125116-23-6叶菌唑Fungalergosterol biosynthesistoxin biosynthesis genes14α-demethylaseFusarium crown rotwheatABC transporter genesmycelial growthconidial germ tube elongationantioxidant enzyme activitiesFusarium pseudograminearumInhibitorinhibitorinhibit

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