2. Protein Tyrosine Kinase/RTK
  3. Syk
  4. MK-8457

MK-8457 是脾酪氨酸激酶 (SYK) 和 ζ 链相关蛋白激酶 70 (ZAP70) 的双重抑制剂。MK-8457 可用于类风湿性关节炎、高血压的相关研究。

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MK-8457

MK-8457 Chemical Structure

CAS No. : 1312518-85-6

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MK-8457 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MK-8457 is a dual inhibitor of spleen tyrosine kinase (SYK) and zeta-chain-associated protein kinase 70 (ZAP70). MK-8457 can be used for the researches of rheumatoid arthritis, hypertension[1].

体外研究
(In Vitro)

MK-8457 正针对类风湿关节炎开展 2 期临床试验研究，后因严重感染终止；同时已完成针对高血压受试者降血压的 1 期临床试验评估[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

MK-8457 相关抗体:
分子量

506.54

Formula

C24H25F3N4O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MK-8457 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MK-84571312518-85-6MK8457MK 8457SykSpleen tyrosine kinaseZAP70SYKrheumatoid arthritishypertensive participantshypertensionspleen tyrosine kinasezeta-chain-associated protein kinase 70Inhibitorinhibitorinhibit

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