1. Apoptosis
  2. Bcl-2 Family
  3. MS1 peptide

MS-1 peptide 是一种用于 BH3 谱分析的肽段。MS-1 peptide 可使经 Encorafenib (HY-15605) 预处理的黑色素瘤细胞线粒体膜去极化程度升高。MS1 peptide 可用于 BRAFV600E 黑色素瘤的相关研究。

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Custom Peptide Synthesis

MS1 peptide

MS1 peptide Chemical Structure

CAS No. : 1875102-20-7

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MS-1 peptide is a peptide for BH3 profiling. MS-1 peptide triggers higher depolarization of mitochondrial membrane in melanoma cells pre-treated with Encorafenib (HY-15605). MS1 peptide can be used for the research of BRAFV600E melanoma[1].

IC50 & Target[1]

Bcl-2

 

体外研究
(In Vitro)

MS1 peptide (4-8 μM) 可显著增加经 Encorafenib 预处理的 DMBC11、DMBC12、DMBC21、DMBC28 和 DMBC29 株 BRAFV600E 黑色素瘤细胞的线粒体膜去极化水平[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

2850.22

Formula

C126H197N39O35S

CAS 号
Sequence

Ac-Arg-Pro-Glu-Ile-Trp-Met-Thr-Gln-Gly-Leu-Arg-Arg-Leu-Gly-Asp-Glu-Ile-Asn-Ala-Tyr-Tyr-Ala-Arg-NH2

Sequence Shortening

Ac-RPEIWMTQGLRRLGDEINAYYAR-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MS1 peptide
目录号:
HY-P11706
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