功能性片段库

半胱氨酸靶向共价片段库

Cysteine Targeted Covalent Fragment Library

Compound library containing fragments with various warheads targeting cysteine residue.

靶向赖氨酸的共价片段库

Lysine Focused Covalent Fragment Library

This fragment library containing 445 fragments with warheads targeting lysine residue.

共价片段库

Covalent Fragment Library

This fragment library containing fragments with various warheads targeting different covalent residues.

靶向酪氨酸的共价片段库

Tyrosine Focused Covalent Fragment Library

This fragment library containing 124 fragments with warheads targeting tyrosine residue.

激酶铰链结合片段库

MCE Kinase Hinge Binder Fragment Library

MCE kinase hinge-binding fragment library derived from kinase inhibitors, is optimized for hinge region binding and key amino acid interactions through molecular docking and pharmacophore constraints, making it a highly effective tool for screening and developing drugs targeting kinases.

高溶解性片段库

Fragment Library with Good Solubility

A compound library with experimentally validated good solubility via kinetic solubility testing can be used for the scaffold design and activity screening of subsequent drug molecules.

靶向丝氨酸/苏氨酸的共价片段库

Serine/Threonine Focused Covalent Fragment Library

This fragment library containing 3,300 fragments with warheads targeting serine and threonine residues.