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  4. Triethylene glycol diacetate

Triethylene glycol diacetate  (Synonyms: 三乙二醇二乙酸酯)

目录号: HY-W102352
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Triethylene glycol diacetate 是一种具有口服活性的 Triethylene glycol (HY-W017440) 衍生物，具有生殖毒性。Triethylene glycol diacetate 在哺乳期可降低哺乳期小鼠幼崽的体重，但其影响在青年成年期可逆转，并增加成年动物的肾/肾上腺联合重量。Triethylene glycol diacetate 可用于生殖发育毒性的研究。

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Triethylene glycol diacetate

Triethylene glycol diacetate Chemical Structure

CAS No. : 111-21-7

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规格 价格 是否有货 数量
10 mg ￥172
In-stock
25 mg ￥310
In-stock
50 mg ￥468
In-stock
100 mg ￥708
In-stock
500 mg ￥1415
In-stock
1 g ￥2167
In-stock
5 g   询价  
10 g   询价  

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Triethylene glycol diacetate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Triethylene glycol diacetate is an orally active Triethylene glycol (HY-W017440) derivative with reproduction toxicity. Triethylene glycol diacetate reduces body weights of nursing mouse pups during lactation, with effects reversing by young adulthood, and increases combined kidney/adrenal weight in adult. Triethylene glycol diacetate can be used for the research of reproductive and developmental toxicity[1].

体内研究
(In Vivo)

Triethylene glycol diacetate (Compound TGD) (1.36-5.45 g/kg；经饮水给予；持续 98 天) 对 Swiss CD-1 小鼠无生殖毒性，但在最高剂量 (5.45 g/kg) 下可诱导可逆性发育毒性 (出生后第 14 天和第 21 天幼崽体重降低)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Swiss CD-1 (outbred Swiss albino, COBS Cr 1 CD-1 (ICR)BR, 6 weeks of age)[1]
Dosage: 1.36, 2.74, 5.45 g/kg
Administration: In drinking water; 98 days
Result: Observed no effects on fertility or reproductive performance (number of litters per pair, live pups per litter, proportion of pups born alive, live pup weight at birth) at doses up to 3%.
Reduced pup body weights significantly in the 3% group on Postnatal days 14 and 21, with no difference apparent by day 74.
Increased combined kidney/adrenal weight significantly in F1 males and females exposed to 5.45 g/kg.
Observed no effects on sperm motility, concentration, or morphology in F1 males exposed to 5.45 g/kg.
Had no significant effect on the proportion of detected matings or fertile pairs, live F2 pups per litter, proportion of F2
pups born alive, sex of F2 pups born alive, or live F2 pup
weight.
分子量

234.25

Formula

C10H18O6
CAS 号
性状

液体（密度：1,12 g/cm3）

中文名称

三乙二醇二乙酸酯
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Store at room temperature, keep dry and cool

In solvent -80°C 1 year
-20°C 6 months
纯度 & 产品资料
参考文献

Triethylene glycol diacetate 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Triethylene glycol diacetate111-21-7三乙二醇二乙酸酯Drug DerivativeDrug derivativeSwiss CD-1 micereproductive toxicitynursing mouse pupskidney/adrenal weightdevelopmental toxicantInhibitorinhibitorinhibit

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