2. Membrane Transporter/Ion Channel
  3. SGLT
  4. WAY-123783

WAY-123783 是一种强效、选择性且具有口服活性的钠依赖性葡萄糖协同转运蛋白 2 (SGLT2) 抑制剂，经代谢后产生活性。WAY-123783 能够增加 db/db 小鼠的尿糖排泄，同时降低血糖水平 (ED50 值为 9.85 mg/kg)。WAY-123783 物质可用于代谢性疾病的研究，如糖尿病。

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WAY-123783

WAY-123783 Chemical Structure

CAS No. : 152595-59-0

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WAY-123783 相关抗体

Top Publications Citing Use of Products

查看 SGLT 亚型特异性产品:

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SGLT1 SGLT2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

WAY-123783 is a potent, selective and orally active sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor producing activity after metabolism. WAY-123783 can increase the excretion of sugar in urine and at the same time lower the blood sugar level in db/db mice (ED50 = 9.85 mg/kg). WAY-123783 can be used for the research of metabolic disease, such as diabetes[1][2].

IC50 & Target[1]

SGLT2

 

分子量

288.29

Formula

C12H11F3N2OS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

WAY-123783 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WAY-123783152595-59-0WAY123783WAY 123783SGLTSodium-dependent glucose cotransporterssodium/glucose cotransporter 2SGLT2db/dbblood sugarurine sugardiabetesInhibitorinhibitorinhibit

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产品名称：
WAY-123783
目录号：
HY-114598
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