95737-68-1 (蚊蝇醚,Pyriproxyfen)

反应条件：

1.1 Reagents: Hydrogen , Tripotassium phosphate Catalysts: Bis(tri-tert-butylphosphine)palladium Solvents: Tetrahydrofuran ; 24 h, 1 atm, 23 °C

参考文献：

Tritiation of aryl thianthrenium salts with a molecular palladium catalyst

Zhao, Da ; Petzold, Roland; Yan, Jiyao ; Muri, Dieter ; Ritter, Tobias, Nature (London, 2021, 600(7889), 444-449

合成路线：1 步

_94%

反应条件：

1.1 Reagents: Sodium hydroxide Solvents: Dimethylformamide ; rt → 50 °C; 50 °C; 50 °C → 110 °C; 8 - 10 h, 110 °C

参考文献：

Preparation of pyriproxyfen

, China, , ,

合成路线：1 步

1617544-18-9

930-70-1

_91%

反应条件：

1.1 Solvents: Toluene ; reflux; 3 h, reflux

参考文献：

New synthesis process of pyriproxyfen

Wang, Qiang; Xu, Liang-zhong, Qingdao Keji Daxue Xuebao, 2012, 33(2), 155-158

合成路线：1 步

_90%

反应条件：

1.1 Reagents: Potassium hydroxide ; rt → 60 °C; 60 °C
1.2 Reagents: Water ; cooled

参考文献：

Study on synthesis of pyriproxyfen

He, Xi-hui; Ma, Meng-lin; Yuan, Hong-jun; Huang, Xiao-hua; Ye, Yong-qiang, Xihua Daxue Xuebao, 2007, 26(4), 34-35

合成路线：1 步

119613-45-5

_90%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethyl acetate

参考文献：

Synthesis of tritium-labeled fenoxycarb and S-31183, two phenoxyphenyl ether insect growth regulators

Boehm, Marcus F.; Prestwich, Gleen D., Journal of Labelled Compounds and Radiopharmaceuticals, 1988, 25(9), 1007-15

合成路线：1 步

_87%

反应条件：

1.1 Catalysts: Potassium hydroxide Solvents: Ethylene glycol diethyl ether ; rt → 124 °C; 3 h, 124 °C

参考文献：

Method for preparing pyriproxyfen as insect growth regulator

, China, , ,

合成路线：1 步

_86%

反应条件：

1.1 Reagents: Potassium hydroxide Solvents: Water ; rt; rt → 60 °C; 60 °C → 10 °C
1.2 10 °C; 4 h, 10 - 20 °C
1.3 Reagents: Potassium hydroxide Solvents: Toluene ; 50 °C → 80 °C
1.4 80 °C

参考文献：

A method for preparing pyriproxyfen

, China, , ,

合成路线：1 步

_86%

反应条件：

1.1 Reagents: Potassium hydroxide Solvents: Toluene ; rt → 80 °C; 80 °C

参考文献：

Synthetic method of pyriproxyfen

, China, , ,

合成路线：1 步

_86%

反应条件：

1.1 Reagents: Potassium hydroxide Solvents: Dimethylformamide ; rt → 120 °C
1.2 120 °C; 4 h, 120 °C

参考文献：

Synthesis of pyriproxyfen

Gao, Yonghong; Tao, Jianwei; Lu, Qingning, Huaxue Shijie, 2006, 47(6), 366-370

合成路线：1 步

_85%

反应条件：

1.1 Reagents: Potassium hydroxide Solvents: Diethylene glycol ; rt → 80 °C; 4 h, 80 - 120 °C

参考文献：

Method for separating and purifying pyriproxyfen

, China, , ,

合成路线：1 步

反应条件：

1.1 Reagents: Sodium hydride Catalysts: Tetrabutylammonium bromide Solvents: Dimethylformamide ; 0 °C
1.2 0 °C; 0 °C → 85 °C; 5 h, 85 °C
1.3 Reagents: Methanol

参考文献：

Preparation of 1-(4-phenoxyphenoxy)-2-propanol, a key intermediate for pyriproxyfen synthesis

, China, , ,

合成路线：1 步

2320491-88-9

反应条件：

1.1 Reagents: Trifluoroacetic acid Solvents: Dichloromethane ; rt

参考文献：

Site-selective and versatile aromatic C-H functionalization by thianthrenation

Berger, Florian; Plutschack, Matthew B.; Riegger, Julian; Yu, Wanwan; Speicher, Samira; et al, Nature (London, 2019, 567(7747), 223-228

合成路线：1 步

反应条件：

1.1 Reagents: Sodium hydride Solvents: Dimethylformamide ; 50 - 60 °C; 50 - 60 °C; 5 h, 100 °C

参考文献：

Crystal form of pyriproxyfen, its preparation method and use thereof

, China, , ,

合成路线：1 步

反应条件：

1.1 Reagents: Potassium hydroxide Solvents: Toluene ; 50 - 70 °C; 70 °C; > 1 h, 70 °C

参考文献：

Process for synthesis of pyriproxyfen

, China, , ,

合成路线：1 步

反应条件：

1.1 Reagents: Sodium hydride

参考文献：

Nitrogen-containing heterocyclic compounds and their use

, United Kingdom, , ,

合成路线：1 步

参考文献：

Thiadiazolyl oxime ether methoxy acrylate derivative, synthesis method and application thereof

, China, , ,

合成路线：1 步

参考文献：

Preparation of (pyridyloxy)alkyl phenoxyphenyl ethers and analogs as flea killers

, Germany, , ,

合成路线：1 步