（+）-生物素4-氨基苯甲酸钠盐

英文别名 102418-74-6|(+)-Biotin 4-Amidobenzoic Acid, Sodium Salt|Biotin 4-amidobenzoic acid sodium salt|Benzoic acid, 4-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-, sodium salt (1:1)|sodium;4-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4
英文名称 (+)-Biotin 4-Amidobenzoic Acid, Sodium Salt
储存温度 -20°C储存
运输条件 超低温冰袋运输
产品介绍 （+）-生物素4-氨基苯甲酸钠盐是用于测定生物素酶活性的荧光底物。（+）-生物素4-氨基苯甲酸钠被生物素酶水解，其裂解生物素酰胺以在体内产生生物素。生物素是某些羧化酶的必需辅酶，用于修饰组蛋白和调节基因转录。（+）-生物素4-氨基苯甲酸钠盐释放4-氨基苯甲酸（PABA），可通过荧光或比色法对其进行定量。具有（+）-生物素4-氨基苯甲酸钠盐的这项技术用于生物素酶活性测定中，以筛选新生儿是否存在生物素酶缺乏症。 (+)-Biotin 4-Amidobenzoic Acid, Sodium Salt is a fluorogenic substrate for the determination of Biotinidase activity. (+)-Biotin 4-Amidobenzoic Acid, Sodium Salt is hydrolyzed by biotinidase, which cleaves biotin amide to give biotin in vivo. Biotin, an essential coenzyme for certain carboxylases, is used to modify histones and regulate gene transcription. (+)-Biotin 4-Amidobenzoic Acid, Sodium Salt releases 4-aminobenzoic acid (PABA) which is able to be quantified by either fluorescent or colorimetric methods. This technique with (+)-Biotin 4-Amidobenzoic Acid, Sodium Salt is used in biotinidase activity assays to screen newborns for biotinidase deficiency.