泽布拉林

别名 1-(β-D-呋喃核糖基)-1,2-二氢嘧啶-2-酮|2-嘧啶酮-1-β- D -核苷|4-脱氧尿苷
英文别名 Zebularine|3690-10-6|4-Deoxyuridine|Pyrimidin-2-one ribonucleoside|Pyrimidin-2-one beta-ribofuranoside|Pyrimidin-2-one beta-D-ribofuranoside|NSC 309132|CHEBI:46938|1-beta-D-ribofuranosyl-2(1H)-pyrimidinone|1-beta-D-ribofuranosylpyrimidin-2(1H)-one|7A9Y5SX
规格或纯度 ≥98% (HPLC)
英文名称 Zebularine 生化机理 Zebularine is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent.DNA methyltransferase( DNMT) inhibitor and cytidine deaminase inhibitor (K i = 2 µM). Inhibits tumour growth in vitro and in vivo . 应用 An inhibitor of DNA methyltransferase
储存温度 2-8°C储存
运输条件 冰袋运输 备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍 Zebularine is a cell-permeable chemically stable cytidine analog and DNA methylation inhibitor which acts by forming a covalent complex with DNMT. It displays antiangiogenic activity and markedly inhibits vessel formation in different tumor models. It reactivates silenced E-cadherin and potentiates the effects of other epigenetic therapeutics such as vorinistat. Induces differentiation of mesenchymal cells into cardiomyocytes. Inhibits cytidine deaminase (CDD).An inhibitor of DNA methyltransferase Zebularine is a cell-permeable chemically stable cytidine analog and DNA methylation inhibitor which acts by forming a covalent complex with DNMT. It displays antiangiogenic activity and markedly inhibits vessel formation in different tumor models. It reactivates silenced E-cadherin and potentiates the effects of other epigenetic therapeutics such as vorinistat. Induces differentiation of mesenchymal cells into cardiomyocytes. Inhibits cytidine deaminase (CDD). An inhibitor of DNA methyltransferase