产品编号:C183490
化学名称:Cariprazine
别名:N'-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea; RGH 188;
CAS号:839712-12-8
分子式:C₂₁H₃₂Cl₂N₄O
Appearance:Off-White to Light Beige Solid
Melting Point:>180°C (dec.)
分子量:427.41
存储条件:-20°C
溶解度:DMSO (Slightly), Methanol (Slightly)
类别:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:Cariprazine is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.
参考文献:(1) Gruender, G.: Curr. Opin. Invest. Drugs, 11, 823 (2010)
(2) Seneca, N. et al.: Psychopharmacology, 218, 579 (2011)
(3) Kiss, B. et al.: J. Pharmacol. Exp. Therap., 333, 328 (2010)
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