产品货号：A168385
产品名称：1-Acetyl-5-(2-aminopropyl)indoline-7-carbonitrile
Synonyms:1-Acetyl-5-(2-aminopropyl)-2,3-dihydro-1H-Indole-7-carbonitrile
CAS号：175837-01-1
分子式：C₁₄H₁₇N₃O
Appearance:Brown Solid
Melting Point:>83ºC (dec.)
分子量：243.3
Storage:4°C, Hygroscopic
Solubility:Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines;
应用：1-Acetyl-5-(2-aminopropyl)indoline-7-carbonitrile is an intermediate in the synthesis of Silodosin (S465000), an a1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy.
参考文献：Barve, I.J., et. al.: Tetrahedron, 69, 2834 (2013); Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995); Murata, S., et al.: J. Urol., 164, 578 (2000)
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