CAS:1034301-08-0|4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-b-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one

产品货号：A601705
产品名称：4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-b-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one
Synonyms:β-Decitabine-3',5'-bis(4-chlorobenzoate); Decitabine USP Related Compound B
Impurity:Decitabine USP Related Compound B
CAS号：1034301-08-0
分子式：C₂₂H₁₈Cl₂N₄O₆
Appearance:White Solid
Melting Point:>182°C (dec.)
分子量：505.31
Storage:-20°C
Solubility:Chloroform (Very Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用：4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-b-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one (Decitabine USP Related Compound B) is a derivative of b-Decitabine (A796950) which is used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines.
参考文献：Deng, T., et al.: Life Sci., 84, 311 (2009), Horne, H., et al.: Mol. Cancer Res., 7, 199 (2009), Zinner, R., et al.: Mol. Cancer Ther., 8, 521 (2009)
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