CAS:165049-28-5|N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid 1,5-Diethyl Ester 4-Methylbenzenesulfonate

产品货号：A605005
产品名称：N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid 1,5-Diethyl Ester 4-Methylbenzenesulfonate
CAS号：165049-28-5
分子式：C₃₁H₃₇N₅O₉S
Appearance:Off-White to Pale Brown Solid
Melting Point:>192ºC (dec.)
分子量：655.72
Storage:4°C
Solubility:Dichloromethane (Very Slightly), DMF (Slightly, Sonicated), DMSO (Slightly)
Category:Standards; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
应用：N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid 1,5-Diethyl Ester 4-Methylbenzenesulfonate is used in the preparation of Pemetrexed (A604980) Sodium. Pemetrexed, is used in the treatment of malignant pleural mesothelioma (MPM).
参考文献：Pasello, G. et al.: Anticanc. Res., 32, 5393 (2012);
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