产品货号：B415095
产品名称：N,N-Bis-desethyl, N-Methyl Entacapone
Synonyms:(2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methyl-2-propenamide;
CAS号：1364322-41-7
分子式：C₁₁H₉N₃O₅
分子量：263.21
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用：N,N-Bis-desethyl, N-Methyl Entacapone is an impurity of Entacapone (E558500). The (E)-Isomer of Entacapone which is a polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
参考文献：Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),
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