产品货号：A808125
产品名称：AZD 7762
同义名称：3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-thiophenecarboxamide; N-[(S)-piperidin-3-yl]amide-5-(3-Fluorophenyl)-3-ureidothiophene-2-carboxylic Acid;
CAS 号:860352-01-8
分子式：C₁₇H₁₉FN₄O₂S
分子量：362.42
产品类别：Standards; Enzyme Activators and Inhibitors;
产品应用：AZD 7762 is studied as an cancer therapeutic agent due to its selective inhibitory activities towards checkpoint kinases, chk1 and chk2 by reversibly binding their respective ATP-binding sites within tumor cells. Recent research has also indicated AZD 7762 to possess enhancing effects towards other chk1 inhibitor lethality in glioblastoma cells.
参考文献:Sonya, D.Z., et al.: Mol Cancer Ther., 7, 2955 (2006); Tang, D., et al.: Cancer. Bio. Ther., 13, 379 (2012);
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