产品货号：A794776
产品名称：Avapritinib
同义名称：(1S)-1-(4-fluorophenyl)-1-(2-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl}pyrimidin-5-yl)ethan-1-amine; Avapritinib; Ayvakit; Ayvakyt; BLU 285;(αS)-α-(4-Fluorophenyl)-α-methyl-2-[4-[6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]-1-piperazinyl]-5-pyrimidinemethanamine;
CAS 号:1703793-34-3
分子式：C₂₆H₂₇FN₁₀
分子量：498.56
产品类别：Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：Avapritinib is a medication used for the treatment of tumors due to one specific rare mutation. Avapritinib is a potent, selective, and orally active KIT and PDGFRA activation loop mutant kinases inhibitor.
参考文献:Vallilas, C., et al.: Int. J. Mol. Sci., 22, 493 (2021); Jones, R. L., et al.: Eur. J. Cancer, 145, 132 (2021)
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