1. Anti-infection
  2. Bacterial
  3. 1-Hydroxy-3,5-dimethoxyxanthone

1-Hydroxy-3,5-dimethoxyxanthone 是一种呫吨酮类化合物和抗菌 (Antibacterial) 剂。1-Hydroxy-3,5-dimethoxyxanthone 可从 Lomatogonium rotatum 中分离得到。1-Hydroxy-3,5-dimethoxyxanthone 可抑制 Pseudomonas aeruginosa ATCC27853 和 Escherichia coli ATCC25923 的生长,其 MIC 为 640 μg/mL。1-Hydroxy-3,5-dimethoxyxanthone 对宫颈癌、乳腺癌、黑色素瘤、肝癌和胃癌均表现出抗癌活性。

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1-Hydroxy-3,5-dimethoxyxanthone

1-Hydroxy-3,5-dimethoxyxanthone Chemical Structure

CAS No. : 6563-48-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

1-Hydroxy-3,5-dimethoxyxanthone is a xanthone and Antibacterial agent. 1-Hydroxy-3,5-dimethoxyxanthone can be isolated from Lomatogonium rotatum. 1-Hydroxy-3,5-dimethoxyxanthone inhibits the growth of Pseudomonas aeruginosa ATCC27853 and Escherichia coli ATCC25923 with an MIC of 640 μg/mL. 1-Hydroxy-3,5-dimethoxyxanthone exhibits anticancer activity against cervical cancer, breast cancer, melanoma, liver cancer, and gastric cancer[1].

体外研究
(In Vitro)

1-Hydroxy-3,5-dimethoxyxanthone (48 h) 可在体外抑制 HeLa、MCF-7、A375-S2、HepG2 和 SGC-7901 细胞的生长,对 SGC-7901 细胞的活性最强 (IC50 = 48.74 μg/mL)[1]
1-Hydroxy-3,5-dimethoxyxanthone (1.25-640 μg/mL; 24 h) 可在体外抑制铜绿假单胞菌 ATCC27853 和大肠杆菌 ATCC25923 的生长,MIC 为 640 μg/mL[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

272.25

Formula

C15H12O5

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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1-Hydroxy-3,5-dimethoxyxanthone
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