2. Others
  3. Drug Derivative
  4. 9-O-Angeloyl-8-methoxythymol

9-O-Angeloyl-8-methoxythymol (compound 5) 是一种麝香草酚衍生物和细胞毒素，对人髓系白血病细胞的 IC50 值为 13.1 μg/mL，对人淋巴母细胞白血病细胞的 IC50 值为 31.8 μg/mL，对结肠癌和淋巴瘤细胞的 IC50 >40 μg/mL。\n9-O-Angeloyl-8-methoxythymol 可用于白血病相关的研究。

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9-O-Angeloyl-8-methoxythymol

9-O-Angeloyl-8-methoxythymol Chemical Structure

CAS No. : 361541-62-0

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9-O-Angeloyl-8-methoxythymol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

9-O-Angeloyl-8-methoxythymol (compound 5) is a thymol derivative and cytotoxin, with a IC50 value of 13.1 μg/mL against human myeloid leukemia cells, a IC50 value of 31.8 μg/mL against human lymphoblastic leukemia cells, and a IC50 >40 μg/mL against colon cancer and lymphoma cells.\n9-O-Angeloyl-8-methoxythymol is applicable to leukemia-related research[1].

体外研究
(In Vitro)

9-O-Angeloyl-8-methoxythymol (8-concentration, 128-fold range; 3 days) 可在 CCRF-CEM 和 HL-60 细胞系中诱导细胞毒性，其 IC50 值分别为 31.8 μg/mL 和 13.1 μg/mL；且在浓度高达 40 μg/mL 时，对 DLD-1 和 P388D1 细胞系无细胞毒性作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

9-O-Angeloyl-8-methoxythymol 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: DLD-1 (human colorectal carcinoma), CCRF-CEM (human lymphoblastic leukemia), HL-60 (human myeloid leukemia), P388D1 (murine macrophage-like lymphoma)
Concentration: 8-concentration, 128-fold range
Incubation Time: 3 days
Result: Exhibited an IC50 value of 31.8 μg/mL against CCRF-CEM cells.
Showed an IC50 value of 13.1 μg/mL against HL-60 cells.
Demonstrated no cytotoxicity (IC50 >40 μg/mL) against DLD-1 and P388D1 cells.
分子量

278.34

Formula

C16H22O4
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

9-O-Angeloyl-8-methoxythymol 相关分类

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Keywords:

9-O-Angeloyl-8-methoxythymol361541-62-0Drug DerivativeDrug derivativelymphoid cancer cellsEupatorium cannabinum ssp. asiaticumhuman lymphoblastic leukemia cellsDLD-1 cell linesCCRF-CEM cell lineshuman lymphoblastic leukemiacolon cancer cellshuman myeloid leukemiaHL-60 cell lineshuman myeloid leukemia cellsInhibitorinhibitorinhibit

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