2. Others Anti-infection Metabolic Enzyme/Protease
  3. Drug Isomer Bacterial Fungal Carboxypeptidase
  4. α-Thujaplicin

α-Thujaplicin 是 Hinokitiol (HY-B2230) 的异构体，是一种抗菌 (antimicrobial) 剂。α-Thujaplicin 可从 Aomori Hiba (Thujopsis dolabrata SIEB. et ZUCC. var. hondai MAKINO) 中分离得到。α-Thujaplicin 可抑制 Carboxypeptidase A (IC50：32.4 μM)。α-Thujaplicin 对七种植物病原真菌表现出较强的抗真菌 (antifungal) 活性，其 MIC 范围为 12.0-50.0 μg/mL。α-Thujaplicin 对嗜肺军团菌 SG 1 和嗜肺军团菌 SG 3 菌株具有抗菌 (antibacterial) 活性，其 MIC 值在 12.5-50 μg/mL 范围内。α-Thujaplicin 对粪肠球菌 IFO-12965 菌株也具有抗菌活性，MIC 值为 1.56 μg/mL。α-Thujaplicin 对稗草种子萌发具有抑制作用。α-Thujaplicin 可抑制淋巴细胞白血病、胃癌和艾氏腹水癌。

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α-Thujaplicin

α-Thujaplicin Chemical Structure

CAS No. : 1946-74-3

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α-Thujaplicin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

α-Thujaplicin, the isomer of Hinokitiol (HY-B2230), is an antimicrobial agent. α-Thujaplicin can be isolated from Aomori Hiba (Thujopsis dolabrata SIEB. et ZUCC. var. hondai MAKINO). α-Thujaplicin shows inhibition of Carboxypeptidase A (IC50: 32.4 μM). α-Thujaplicin shows rather strong antifungal activity against seven kinds of plant-pathogenic fungi, their MICs being in the range of 12.0-50.0 μg/mL. α-Thujaplicin shows clear antibacterial activity against Legionella pneumophila SG 1 and L. pneumophila SG 3, and their MICs are in the range of 12.5-50 μg/mL. α-Thujaplicin shows antibacterial activity against Enterococcus faecalis IFO-12965 with a MIC of 1.56 μg/mL. α-Thujaplicin shows germination inhibition toward the seed of Echinochloa utilis Ohwi et Yabuno. α-thujaplicin inhibits lymphocytic leukemia, stomach cancer, Ehrlich’s ascites carcinoma[1][2].

IC50 & Target

IC50: 32.4 μM (Carboxypeptidase A)[2]
分子量

164.20

Formula

C10H12O2
CAS 号
中文名称

α-侧柏素
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

α-Thujaplicin 相关分类

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Keywords:

α-Thujaplicin1946-74-3α-侧柏素Drug IsomerBacterialFungalCarboxypeptidaseInhibitorinhibitorinhibit

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