2. Immunology/Inflammation
  3. Transmembrane Glycoprotein
  4. Anti-Mouse CD90.2 Antibody (30H12)

Anti-Mouse CD90.2 Antibody (30H12) 

目录号: HY-P99131
一键复制产品信息 纯度: 95.00%
COA 技术支持

Anti-Mouse CD90.2 Antibody (30H12) 是一种源自大鼠宿主的抗小鼠 CD90.2 IgG2b 抗体抑制剂。Anti-Mouse CD90.2 Antibody (30H12) 可消耗固有淋巴细胞 (ILC) 和 T 细胞。Anti-Mouse CD90.2 Antibody (30H12) 可用于感染、炎症和免疫学研究，如小肠结肠炎耶尔森菌 (Yersinia enterocolitica) 感染和气道炎症。

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Anti-Mouse CD90.2 Antibody (30H12)

Anti-Mouse CD90.2 Antibody (30H12) Chemical Structure

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规格 价格 是否有货 数量
1 mg ￥570
In-stock
5 mg ￥2350
In-stock
10 mg ￥4600
In-stock
50 mg   询价  
100 mg   询价  

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Anti-Mouse CD90.2 Antibody (30H12) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse CD90.2 Antibody (30H12) is an anti-mouse CD90.2 IgG2b antibody inhibitor derived from host Rat. Anti-Mouse CD90.2 Antibody (30H12) can deplete innate lymphoid cells (ILC) and T cells. Anti-Mouse CD90.2 Antibody (30H12) can be used for the researches of infection, inflammation and immunology, such as Yersinia enterocolitica infection and airway inflammation[1][2].

同型

Rat IgG2b kappa
推荐同型对照抗体
反应种属

Human/Mouse
体内研究
(In Vivo)

Anti-Mouse CD90.2 Antibody (30H12) (100 μg/mouse，腹腔注射，在第 -4, -1, 2, 5 天给药) 可清除先天性淋巴细胞 (ILC)，并降低感染小肠结肠炎耶尔森菌的 Rag1−/− 小鼠的存活率[1]。
Anti-Mouse CD90.2 Antibody (30H12) (500 μg/mouse，腹腔注射，每隔一天一次，共 4 次) 可清除 2 型先天性淋巴细胞 (ILC2)，并减轻臭氧诱导小鼠的气道炎症和高反应性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rag1−/− mice with Yersinia enterocolitica infection[1]
Dosage: 500 μg/mouse
Administration: Intraperitoneally injection, at days -4, -1, 2, 5
Result: Depleted ILC and most NK cells in the small intestinal lamina propria.
Had a decreased survival rate and rapid weight loss.
Increased bacterial burden in the ileum, spleen and liver.
Animal Model: Ozone-induced mice[2]
Dosage: 100 μg/mouse
Administration: Intraperitoneally injection, every other day for 4 times
Result: Depleted ILC2 and T cells.
Reduced total cell count and neutrophil and abolished eosinophils in the BAL fluid.
Abolished IL-5 release in the BAL.
应用

in vivo ILC depletion; in vivo T cell depletion; Western blot
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

组分

Please refer to the lot-specific COA for specific buffer information.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 95.00%

COA (245 KB)

抗体抑制剂使用指南 (624 KB)
参考文献

Anti-Mouse CD90.2 Antibody (30H12) 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse CD90.2 Antibody (30H12)Transmembrane GlycoproteinCD90.2Lymphoid cellsT cellsYersinia enterocoliticaIL-5Inhibitorinhibitorinhibit

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