1. 抗体
  2. 一抗
  3. 单克隆抗体
  4. MPO 抗体 (YA5574)

MPO Antibody (YA5574) 是一个小鼠来源、无偶联标记、抗 MPO 的 IgG 单克隆抗体。

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规格 价格 是否有货 数量
20 μL ¥ 595.40

¥916.00

1 - 2 周
50 μL ¥ 887.25

¥1365.00

1 - 2 周
100 μL ¥ 1433.25

¥2205.00

1 - 2 周
250 μL   询价  

* Please select Quantity before adding items.

  • WB: 蛋白质免疫印迹;
  • IHC-P: 石蜡切片样本的免疫组织化学;
  • IHC-F: 冰冻切片样本的免疫组织化学;
  • ICC/IF: 细胞免疫荧光;
  • IF-Tissue: 组织免疫荧光;
  • mIHC: 多重荧光免疫组化;
  • IP: 免疫沉淀;
  • ChIP: 染色质免疫沉淀;
  • FC: 流式细胞术;
  • ELISA: 酶联免疫吸附试验
  • 产品详情

  • 验证图片

  • 背景信息

  • 产品资料

描述

MPO Antibody (YA5574) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to MPO.

宿主

Mouse

克隆性

Monoclonal

分子量
Predicted band size: 84 kDa;
Observed band size: 70 kDa
请注意:因蛋白存在修饰或聚体等情况,以实测为准,预测仅为参考。
反应种属
Human, Mouse, Rat
蛋白数据库
基因 ID
免疫原

Synthesized peptide derived from human Myeloperoxidase(MPO) AA range: 350-450

应用 & 推荐
稀释比例
应用 稀释比
IHC-P
IHC-P: 石蜡切片样本的免疫组织化学
1:200-1000
WB
WB: 蛋白质免疫印迹
1:500-2000
ICC/IF
ICC/IF: 细胞免疫荧光
1:100-500
ELISA
ELISA: 酶联免疫吸附试验
1:1000-5000
纯度 Protein G 偶联 Non-conjugated
修饰 Unmodified 同型 IgG
性状

液体

组分

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

保存条件 & 期限

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

运输条件

Shipping with blue ice.

验证图片
IHC-P
  • Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using Myeloperoxidase(MPO) (PTR2562) Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using Myeloperoxidase(MPO) (PTR2562) Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

背景
功能:髓过氧化物酶 (MPO) 是多形核白细胞宿主防御系统的一部分,负责对多种微生物发挥杀菌活性。在受刺激的 PMN 中,MPO 催化次卤酸 (在生理条件下主要为次氯酸) 和其他毒性中间体的生成,这些物质能显著增强 PMN 的杀菌活性 (PubMed:9922160)。MPO 还介导 α-1-微球蛋白的蛋白水解,生成反式 α-1-微球蛋白 (t-α-1-微球蛋白),后者能有效抑制低密度脂蛋白颗粒的氧化,从而减少血管损伤 (PubMed:25698971)。
亚细胞定位:溶酶体
异构体 & 翻译后修饰:P05164 有 3 个异构体:P05164-1:83869 Da (预测);P05164-2:73854 Da (预测);P05164-3:87248 Da (预测)。
亚基:同源二聚体;二硫键连接。每个单体由一条轻链和一条重链组成。与 CP 和 LTF 形成复合物;直接与 CP 相互作用,通过 MPO 保护 CP 的抗氧化特性 (PubMed:23843990)。
中文名
MPO 抗体 (YA5574)
同用名
84 kDa myeloperoxidase antibody; 89 kDa myeloperoxidase antibody; EC1.11.2.2 antibody; fj80f04 antibody; MPO antibody; mpx antibody; myeloid-specific peroxidase antibody; Myeloperoxidase antibody; Myeloperoxidase heavy chain antibody; Myeloperoxidase light chain antibody; PERM_HUMAN antibody; wu:fj80f04 antibody
文件资料

MPO Antibody (YA5574) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MPO Antibody (YA5574)
目录号:
HY-P85882
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