2. Anti-infection
  3. Parasite
  4. Antimalarial agent 59

Antimalarial agent 59 是一种抗疟剂。Antimalarial agent 59 以 46 nM 的 IC50 抑制耐 Chloroquine (HY-17589A) 的恶性疟原虫 FcB1 株的生长。Antimalarial agent 59 还对癌细胞表现出细胞毒活性。Antimalarial agent 59 可用于疟疾和卵巢癌的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Antimalarial agent 59

Antimalarial agent 59 Chemical Structure

CAS No. : 3103602-12-3

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Antimalarial agent 59 相关抗体

Top Publications Citing Use of Products

查看 Parasite 亚型特异性产品:

查看所有亚型
Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antimalarial agent 59 is an antimalarial agent. Antimalarial agent 59 inhibits the growth of Chloroquine (HY-17589A)-resistant FcB1 strain of Plasmodium falciparum with an IC50 of 46 nM. Antimalarial agent 59 also shows cytotoxic activity against cancer cells. Antimalarial agent 59 can be used for the researches of malaria and ovarian cancer[1].

体外研究
(In Vitro)

Antimalarial agent 59 (Compound 5i) (48 h) 可强效抑制耐 Chloroquine (HY-17589A) 的恶性疟原虫 (Plasmodium falciparum) FcB1 株的生长，其 IC50 为 46 nM，选择性指数为 232[1]。
Antimalarial agent 59 (72 h) 可抑制 HeLa 宫颈癌细胞的生长，其 LD50 为 10.85 μM[1]。
Antimalarial agent 59 (1-10 μM; 24-72 h) 可以浓度和时间依赖的方式降低 A2780 卵巢癌细胞的活力，在 10 μM 处理 48 h 和 72 h 后可实现近乎完全的抑制[1]。
Antimalarial agent 59 (1-10 μM; 72 h) 可抑制 A2780 卵巢癌细胞的生长，孵育 72 h 后的 IC50 为 3.82 ± 1.38 μM[1]。
Antimalarial agent 59 (1-10 μM; 24-72 h) 可以浓度和时间依赖的方式降低 A549 肺腺癌细胞的活力，其中在 10 μM 作用 72 h 后观察到最强的抑制效果 (细胞活力为 15.75%)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antimalarial agent 59 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: A2780 ovarian cancer cells
Concentration: 1, 10 μM
Incubation Time: 24, 48, 72 h
Result: Reduced cell viability to 67.38% at 1 μM (24 h).
Reduced cell viability to 79.57% at 1 μM (48 h).
Reduced cell viability to 92.20% at 1 μM (72 h).
Reduced cell viability to 2.19% at 10 μM (24 h).
Reduced cell viability to 0.04% at 10 μM (48 h).
Reduced cell viability to 1.03% at 10 μM (72 h).

Cell Cytotoxicity Assay[1]

Cell Line: A549 lung adenocarcinoma cells
Concentration: 1, 10 μM
Incubation Time: 24, 48, 72 h
Result: Reduced cell viability to 99.03% at 1 μM (24 h).
Reduced cell viability to 92.09% at 1 μM (48 h).
Reduced cell viability to 97.16% at 1 μM (72 h).
Reduced cell viability to 32.81% at 10 μM (24 h).
Reduced cell viability to 19.87% at 10 μM (48 h).
Reduced cell viability to 15.75% at 10 μM (72 h).
分子量

340.37

Formula

C17H24O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antimalarial agent 59 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antimalarial agent 593103602-12-3Antimalarial agent59Antimalarial agent-59ParasitemalariaA549 lung adenocarcinoma cellsovarian cancer cellsPlasmodium falciparumHeLa cervical cancer cellsA2780 ovarian cancer cellschloroquine-resistant FcB1 straincervical cancer cellsovarian cancerInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Antimalarial agent 59
目录号：
HY-181658
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z