2. Anti-infection
  3. SARS-CoV Virus Protease
  4. Artecanin

Artecanin 是一种 SARS-CoV-2 主蛋白酶 (Mpro) 抑制剂，具有预测的高胃肠道吸收性、口服生物利用度，且无预测的肝毒性、致癌性、致突变性或细胞毒性。Artecanin 可与 Mpro 活性位点的关键氨基酸残基 His41 和 Cys145 相互作用，阻断病毒前体蛋白的切割与成熟，并与 Mpro 形成稳定复合物。Artecanin 可阻断 SARS-CoV-2 的入侵。Artecanin 可用于新型冠状病毒肺炎的研究。

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Artecanin

Artecanin Chemical Structure

CAS No. : 29431-84-3

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Artecanin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Artecanin is a SARS-CoV-2 main protease (Mpro) inhibitor with predicted high gastrointestinal absorption and oral bioavailability, and no predicted hepatotoxicity, carcinogenicity, mutagenicity or cytotoxicity. Artecanin interacts with His41 and Cys145, the key amino acid residues in the active site of Mpro, blocks the cleavage and maturation of viral precursor proteins, and forms a stable complex with Mpro. Artecanin blocks the invasion of SARS-CoV-2. Artecanin is applicable to the research of COVID-19[1].

体外研究
(In Vitro)

Artecanin 具有良好的类药属性 (符合所有标准规则、胃肠道吸收率高)，且无预测毒性 (肝毒性、致癌性、致突变性、细胞毒性)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Artecanin 相关抗体:
分子量

278.30

Formula

C15H18O5
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Artecanin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Artecanin29431-84-3SARS-CoVVirus ProteaseSARS coronavirusHis41MproSARS-CoV-2 main proteasecovid-19Cys145Inhibitorinhibitorinhibit

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