2. Others Anti-infection
  3. Drug Derivative Bacterial
  4. Avocadene

Avocadene 是一种从 Persea americana 叶片中分离得到的天然产物，具有抗癌、杀虫、抗幽门螺杆菌 (Helicobacter pylori) 及抗炎活性。Avocadene 通过抑制幽门螺杆菌生长和阻止蛋白质变性发挥抗菌及抗炎作用。Avocadene 对人前列腺癌 PC‑3 细胞表现出显著的细胞毒活性，其 IC50 为 0.5 μg/mL。Avocadene 可用于幽门螺杆菌相关胃肠道炎症、胃十二指肠损伤及前列腺肿瘤的研究。

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Avocadene

Avocadene Chemical Structure

CAS No. : 24607-08-7

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Avocadene 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Avocadene is a natural product isolated from Persea americana leaves, with anticancer, insecticidal, anti-Helicobacter pylori, and anti-inflammatory activity. Avocadene exerts antibacterial and anti‑inflammatory effects by suppressing Helicobacter pylori growth and inhibiting protein denaturation. Avocadene displays obvious cytotoxic activity against human prostate cancer PC‑3 cells with an IC50 of 0.5 μg/mL. Avocadene can be used for research of Helicobacter pylori‑associated gastrointestinal inflammation, gastroduodenal injury and prostate tumors[1][2].

体外研究
(In Vitro)

Avocadene 对人前列腺腺癌 (PC-3) 细胞表现出细胞毒活性，其 IC50 为 0.5 µg/mL[1]。
Avocadene 对黄热病蚊幼虫具有杀虫活性，其 LC50 为 0.2 µg/mL[1]。
Avocadene 具有强效抗幽门螺杆菌活性，抑菌圈直径为 12.9 mm，最低抑菌浓度为 32 μg/mL[2]。
Avocadene 具有显著的抗炎活性，在体外可抑制 22.40% 的蛋白质变性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Avocadene 相关抗体:
分子量

286.45

Formula

C17H34O3
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Avocadene 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Avocadene24607-08-7Drug DerivativeBacterialDrug derivativeHelicobacter pyloriPersea americanahuman prostate adenocarcinomaPC-3 cellsprotein denaturationInhibitorinhibitorinhibit

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