2. Cell Cycle/DNA Damage
  3. DNA Stain
  4. BODi-1

BODi-1 是一种靶向 dsDNA 的荧光调节剂，通过双嵌入的方式与 dsDNA 结合。BODi-1 在结合核酸后出现荧光增强效应，但在更高的染料/DNA 比例下，其荧光强度、各向异性及平均寿命会降低。当 BODi-1 与脂质体复合物中的 DNA 结合时，还会出现发射光谱红移以及量子产率和平均寿命降低的现象。在染料/DNA 比例低于 0.01 时，BODi-1 不会引发显著的 DNA 构象改变。BODi-1 可作为荧光探针应用于脂质体复合物的表征以及该比例下的 FRET 研究。

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BODi-1

BODi-1 Chemical Structure

CAS No. : 169454-13-1

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BODi-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BODi-1 is a dsDNA-targeting fluorescence modulator. BODi-1 bis-intercalates into dsDNA, with no external binding in studied concentration ranges. BODi-1 exhibits large fluorescence enhancement upon nucleic acid binding, with fluorescence intensity, anisotropy, and average lifetime decreasing at higher dye/DNA ratios. BODi-1 shows emission spectrum redshift, plus reduced quantum yield and average lifetime when bound to DNA in lipoplexes. BODi-1 functions as a fluorescent probe for lipoplex characterization and FRET studies at a dye/DNA ratio of 0.01. BODi-1 does not induce considerable DNA conformation modification at dye/DNA ratios below 0.01[1].

体外研究
(In Vitro)

BOBO-1在超螺旋及松弛型 pUC19 DNA 中，当染料/DNA 碱基比 ≤0.01 时，展现出稳定的荧光强度与各向异性 (~0.20)[1]。
BOBO-1 在 pUC19 DNA/DOTAP 脂质复合物中，当染料/DNA 碱基比 ≤0.005 时可维持稳定的荧光各向异性 (~0.20)；在更高比例下，其荧光强度和各向异性会降低[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

BODi-1 相关抗体:
分子量

1202.66

Formula

C41H54I4N6S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BODi-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BODi-1169454-13-1BODi1BODi 1DNA Stainfluorescent probelipoplexessupercoiled pUC19 DNAFRET studiesfluorescence enhancementdsDNAnucleic acidDOTAPrelaxed pUC19 DNAemission spectrumInhibitorinhibitorinhibit

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