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  4. Bruceanic acid D

Bruceanic acid D 是一种苦木素类化合物和细胞毒剂,可从鸦胆子 (Brucea antidysenterica) 的木质部粉末中分离得到。Bruceanic acid D 特异性抑制 P-388 淋巴细胞白血病细胞,而对人肺癌细胞和人结肠癌细胞无活性。Bruceanic acid D 可用于 P-388 淋巴细胞白血病的相关研究。

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Bruceanic acid D

Bruceanic acid D Chemical Structure

CAS No. : 132587-61-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Bruceanic acid D is a quassinoid compound and cytotoxic agent that can be isolated from the xylem powder of Brucea antidysenterica. Bruceanic acid D specifically inhibits P-388 lymphocytic leukemia cells but shows no activity against human lung cancer cells and human colon cancer cells. Bruceanic acid D can be used in studies related to P-388 lymphocytic leukemia[1].

体外研究
(In Vitro)

Bruceanic acid D (compound 5) 对 P-388 小鼠白血病细胞表现出细胞毒活性,其 ED50 为 0.77 μg/mL,且对 A-549 或 HCT-8 细胞无细胞毒活性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

568.57

Formula

C27H36O13

CAS 号
中文名称

鸦胆酸D

结构分类
初始来源

Brucea antidysenterica

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Bruceanic acid D
目录号:
HY-N18086
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