2. Epigenetics
  3. Protein Arginine Deiminase
  4. CAY10729

CAY10729 (Compound 21) 是一种选择性的 PAD2 抑制剂。CAY10729 可抑制中性粒细胞胞外陷阱形成。

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CAY10729

CAY10729 Chemical Structure

CAS No. : 1644666-57-8

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CAY10729 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CAY10729 (Compound 21) is a selective PAD2 inhibitor. CAY10729 inhibits neutrophil extracellular trap formation[1].

IC50 & Target[1]

PAD2

 

体外研究
(In Vitro)

CAY10729 (1-500 μM; 4 h) 对中性粒细胞表现出极低的细胞毒性，其 EC50 为 985 μM[1]。
CAY10729 (200 mM) 抑制中性粒细胞胞外陷阱形成[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CAY10729 相关抗体:

Cell Viability Assay[1]

Cell Line: Human osteosarcoma (U2OS) cells
Concentration: 20 μM
Incubation Time: 72 h
Result: Showed no reduction in U2OS cell viability relative to DMSO-treated controls.
分子量

435.91

Formula

C19H26ClN7O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CAY10729 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CAY107291644666-57-8CAY 10729CAY-10729Protein Arginine DeiminasePeptidylarginine DeiminaseU2OS human osteosarcoma cellsmurine hepatic microsomesPAD2human neutrophilsProtein Arginine Deiminase 2mouse neutrophilsneutrophil extracellular trap formationPAD1PAD isozymeshuman PAD2Inhibitorinhibitorinhibit

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产品名称：
CAY10729
目录号：
HY-181449
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